Protein Alignment Pc and Cbx8

DIOPT Version :10

• Sequence 1: NP_524199.1
• Gene: Pc / 40358
• FlyBaseID: FBgn0003042
• Length: 390
• Species: Drosophila melanogaster
• Sequence 2: NP_001029250.1
• Gene: Cbx8 / 303731
• RGDID: 1565375
• Length: 366
• Species: Rattus norvegicus
• Alignment Length: 408
• Identity: 106/408 - (25%)
• Similarity: 168/408 - (41%)
• Gaps: 104/408 - (25%)

  Fly    25 VYAAEKIIQKRVKKGVVEYRVKWKGWNQRYNTWEPEVNILDRRLIDIYEQTNKSSGT--PSKRGI 87
            |:|||.::::|::||.:||.||||||:|:|:|||||.||||.||:..:|:..:....  |.|||
  Rat    10 VFAAEALLKRRIRKGRMEYLVKWKGWSQKYSTWEPEENILDARLLAAFEEREREMELYGPKKRG- 73

  Fly    88 KKKEKEPDPEPESEEDEYTFTENDVDTHQATTSSATHDKESKKEKKHHHHHHHHHHIKSERNSGR 152
                    |:|:      ||    :...||...:.|::                  .:|:...|.
  Rat    74 --------PKPK------TF----LLKAQAKAKAKTYE------------------FRSDSTRGI 102

  Fly   153 RSESPLTHHHHHHHHESKRQRIDHSSSSNS-SFTHNSFVPEPDSNSSSSEDQPLIGTKRKAEVLK 216
            |...|            .|...|.:|:|.: ....|:.:|.|.|::|:....|.....|..:..:
  Rat   103 RIPYP------------GRSPQDLASTSRAREGLRNTGLPPPGSSTSTCRADPPRDRDRDRDRER 155

  Fly   217 ESGKIGVTIKTSPDGPTIK---PQPTQQVTPSQQQPFQDQQ-------QAEKI-----------A 260
            :.|...|..|.|..|.:.|   |:|.:::....|:|..:..       :..|:           |
  Rat   156 DRGTSRVDEKPSSPGDSSKKRGPKPRKELLDPSQRPLGEPSDGLGEYLKGRKLDETPSGIGKFSA 220

  Fly   261 SEAATQLKSEQQA--------TPLATE-----AINTTPAESGAEEEEVANEEGNQQAPQVPS--- 309
            ..:..||...|.:        :|.:.|     |.:|.||.  ..:...|..|...|....|.
  Rat   221 GHSVIQLARRQDSDLVQYGVTSPSSAEASGKLAADTFPAR--VIKHRAALLEAKGQGALDPGGTR 283

  Fly   310 --ENNNIPKPCNNL-----AINQKQPLTPLSPRAL-----PPRFWLPAKCNISNRVVITDVTVNL 362
              .::..|....:|     |...:..|....|.|.     ....|.|:..|: .:||:||||.|.
  Rat   284 VRHSSGTPGSVGSLYRDMGAQGGRPSLIARIPVARILGDPEEESWSPSLTNL-EKVVVTDVTSNF 347

  Fly   363 ETVTIRECKTERGFFRER 380
            .||||:|..|::|||:|:
  Rat   348 LTVTIKESNTDQGFFKEK 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pc	NP_524199.1	CD_polycomb	23..76	CDD:349291	29/50 (58%)
		CBX7_C	341..373	CDD:465385	15/31 (48%)
Cbx8	NP_001029250.1	CD_polycomb_like	11..59	CDD:349277	27/47 (57%)
		CBX7_C	326..358	CDD:465385	15/32 (47%)