DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pc and Cbx5

DIOPT Version :9

Sequence 1:	NP_524199.1	Gene:	Pc / 40358	FlyBaseID:	FBgn0003042	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_001070257.1	Gene:	Cbx5 / 12419	MGIID:	109372	Length:	191	Species:	Mus musculus

Alignment Length:	128	Identity:	39/128 - (30%)
Similarity:	69/128 - (53%)	Gaps:	22/128 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 GSKGKLGRDNATDDPVDLVYAAEKIIQKRVKKGVVEYRVKWKGWNQRYNTWEPEVNILDRRLIDI 71
            |.|.|...|:::.:..: .|..||::.:|:.||.|||.:||||:::.:||||||.|:....||..
Mouse     2 GKKTKRTADSSSSEDEE-EYVVEKVLDRRMVKGQVEYLLKWKGFSEEHNTWEPEKNLDCPELISE 65

  Fly    72 YEQTNKSSGTPSKRGIKKKEKEPD-PEPESEEDEYTFTENDVDTHQATTSSATHDKESKKEKK 133
            :.:..|          |.||.|.: |..:||.::          .:::.|::..|.:|||:::
Mouse    66 FMKKYK----------KMKEGENNKPREKSEGNK----------RKSSFSNSADDIKSKKKRE 108

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pc	NP_524199.1	CHROMO	25..77	CDD:214605	22/51 (43%)
Cbx5	NP_001070257.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..21		4/19 (21%)
		CD_HP1alpha_Cbx5	19..68	CDD:349298	22/48 (46%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	70..117		13/59 (22%)
		CSD_HP1alpha_Cbx5	116..173	CDD:349302
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1628171at2759
OrthoFinder	1	1.000	-	-		FOG0000191
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920