Protein Alignment CG11309 and SERHL2

DIOPT Version :10

• Sequence 1: NP_649301.1
• Gene: CG11309 / 40356
• FlyBaseID: FBgn0037070
• Length: 358
• Species: Drosophila melanogaster
• Sequence 2: XP_054181421.1
• Gene: SERHL2 / 253190
• HGNCID: 29446
• Length: 342
• Species: Homo sapiens
• Alignment Length: 286
• Identity: 77/286 - (26%)
• Similarity: 125/286 - (43%)
• Gaps: 59/286 - (20%)

  Fly    46 AEISITVPWGHISGKWYGPQNVQPILGLHGWQDNAGTFDRLMPLLSPDVAFLAIDLPGHGLSSRL 110
            :|:.:.||||||:.|.:|.....|:|.||||.|||.:||||:|||..|..::|:|..||||||..
Human    11 SELKLAVPWGHIAAKAWGSLQGPPVLCLHGWLDNASSFDRLIPLLPQDFYYVAMDFGGHGLSSHY 75

  Fly   111 PDGCYYNSVDNLYVIRLIMKQYKWEKVSLVGHSMSSIICFVFAAVFPDKVDMIIGIDA----LKP 171
            ..|..|.....:..||.::              ...::..:|...||:.||.:|.:|.    |:.
Human    76 SPGVPYYLQTFVSEIRRVV--------------AGGVVGGMFFCTFPEMVDKLILLDTPLFLLES 126

  Fly   172 HQRPYPSVIRTMETRLDEFLREDERNRSKNEPPSYTYD--ELIERVYIGTFHSVNKEHCKHLMAR 234
            .:.   ..:.|.:.|..|.:.:.|    .::.||:.:.  :|::|:.....|.  .|.|..|:.:
Human   127 DEM---ENLLTYKRRAIEHVLQVE----ASQEPSHVFSLKQLLQRLLKSNSHL--SEECGELLLQ 182

  Fly   235 NIGKSEKYPDKYF--------------------------FCRDRRLKFYNYAIG--SQELCVEMA 271
            . |.::...:..|                          ..||:||.:...:|.  |:|||....
Human   183 R-GTTKVATEMEFRHVAQAGLELLNSSDPTDSTSQNGLVLNRDQRLAWAENSIDFISRELCAHSI 246

  Fly   272 NRITCPYLFIKAAQSSYFEDKKYYDE 297
            .::....|.|||.. .||:.::.|.|
Human   247 RKLQAHVLLIKAVH-GYFDSRQNYSE 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11309	NP_649301.1	alpha/beta hydrolases	69..324	CDD:473884	68/263 (26%)
SERHL2	XP_054181421.1	MenH	22..>92	CDD:440361	31/69 (45%)