Protein Alignment CG11309 and EPHX4

DIOPT Version :10

• Sequence 1: NP_649301.1
• Gene: CG11309 / 40356
• FlyBaseID: FBgn0037070
• Length: 358
• Species: Drosophila melanogaster
• Sequence 2: NP_775838.3
• Gene: EPHX4 / 253152
• HGNCID: 23758
• Length: 362
• Species: Homo sapiens
• Alignment Length: 291
• Identity: 63/291 - (21%)
• Similarity: 113/291 - (38%)
• Gaps: 55/291 - (18%)

  Fly    70 ILGLHGWQDNAGTFDRLMPLLSPDVAFLAIDLPGHGLSSRLPDGCYYNSVDNLYV-IRLIMKQYK 133
            :|.|||:.:...::...:.....:...:|:||.|:| .:..|.......:|.|.. |:.|:....
Human    96 MLLLHGFPEFWYSWRYQLREFKSEYRVVALDLRGYG-ETDAPIHRQNYKLDCLITDIKDILDSLG 159

  Fly   134 WEKVSLVGHSMSSIICFVFAAVFPDKVDMIIGIDALKPHQRPYPSVIRTMETRLDEFLREDERNR 198
            :.|..|:||....:|.::.|..:|:.|..:|.|:.      |:|:|       ..|::.......
Human   160 YSKCVLIGHDWGGMIAWLIAICYPEMVMKLIVINF------PHPNV-------FTEYILRHPAQL 211

  Fly   199 SKNEPPSYTYDELIERVYIGTF-HSVNK-EHCKHLM---ARNIGKS---------EKYPDKYFFC 249
            .|:   ||.|  ..:..:...| .|:|. :..|||.   :..||:.         |.|  .|.|.
Human   212 LKS---SYYY--FFQIPWFPEFMFSINDFKVLKHLFTSHSTGIGRKGCQLTTEDLEAY--IYVFS 269

  Fly   250 RDRRL----KFYNYAIGSQELCVEMANR-ITCPYLFIKAAQSSYFEDKKYYDEVLDVLLKKPNFE 309
            :...|    ..|.....    |:.:.:. :|.|.|.:.....::.|.:  ..||..:.:|  |:.
Human   270 QPGALSGPINHYRNIFS----CLPLKHHMVTTPTLLLWGENDAFMEVE--MAEVTKIYVK--NYF 326

  Fly   310 YLEV--NGSHHVHMNDPEAIIAPVNNFIQRF 338
            .|.:  ..||.:..:.|:.    ||..|..|
Human   327 RLTILSEASHWLQQDQPDI----VNKLIWTF 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11309	NP_649301.1	alpha/beta hydrolases	69..324	CDD:473884	58/275 (21%)
EPHX4	NP_775838.3	MenH	70..356	CDD:440361	63/291 (22%)