Protein Alignment CG11309 and Mest

DIOPT Version :10

• Sequence 1: NP_649301.1
• Gene: CG11309 / 40356
• FlyBaseID: FBgn0037070
• Length: 358
• Species: Drosophila melanogaster
• Sequence 2: NP_001239221.1
• Gene: Mest / 17294
• MGIID: 96968
• Length: 342
• Species: Mus musculus
• Alignment Length: 370
• Identity: 60/370 - (16%)
• Similarity: 113/370 - (30%)
• Gaps: 137/370 - (37%)

  Fly    34 PRANIW-CSKKYFAEISITVPWGHISGKWYGPQNVQPILGLHG-----------WQDNAGTFDRL 86
            |..:.| .|.|:|....:.:.:....|....|:.|  :| |||           |:.....|.|:
Mouse    45 PALHSWKTSGKFFTYKGLRIFYQDSVGVVGSPEIV--VL-LHGFPTSSYDWYKIWEGLTLRFHRV 106

  Fly    87 MPLLSPDVAFLAIDLPGHGLSSRLPDGCYYNSVDNLYVIRLIMKQYKWE--KVSLVGHSMSSII- 148
                      :|:|..|.|.|.: |....|:..:...::..:::....:  :::|:.|....|:
Mouse   107 ----------IALDFLGFGFSDK-PRPHQYSIFEQASIVESLLRHLGLQNRRINLLSHDYGDIVA 160

  Fly   149 --------------------CFVFAAVFPDKVDMIIGIDALK----------------------- 170
                                |.....:||:....::....||
Mouse   161 QELLYRYKQNRSGRLTIKSLCLSNGGIFPETHRPLLLQKLLKDGGVLSPILTRLMNFFVFSRGLT 225

  Fly   171 ----PHQRPYPSVIRTMETRLDEFLREDERNRSKNEPPSYTYDELIERVYIGTFHSVNKEHCKHL 231
                |:.||..|.:..|...:            :|...:...|.|::  ||
Mouse   226 PVFGPYTRPTESELWDMWAVI------------RNNDGNLVIDSLLQ--YI-------------- 262

  Fly   232 MARNIGKSEKYPDKYFFCRDRRLKFYNYAIGSQELCVEMANRITCPYLFIKAAQSSYFEDKKYYD 296
                               ::|.||....:|:      :|: ::.|..||...    .:....|.
Mouse   263 -------------------NQRKKFRRRWVGA------LAS-VSIPIHFIYGP----LDPINPYP 297

  Fly   297 EVLDV---LLKKPNFEYLEVNGSHHVHMNDPEAIIAPVNNFIQRF 338
            |.|::   .|.:.....|:.:.||:..:.||...:.....||..|
Mouse   298 EFLELYRKTLPRSTVSILDDHISHYPQLEDPMGFLNAYMGFINSF 342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11309	NP_649301.1	alpha/beta hydrolases	69..324	CDD:473884	47/318 (15%)
Mest	NP_001239221.1	MenH	52..341	CDD:440361	57/360 (16%)