DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pzg and si:dkey-154p10.3

DIOPT Version :9

Sequence 1:	NP_001262143.1	Gene:	pzg / 40351	FlyBaseID:	FBgn0259785	Length:	996	Species:	Drosophila melanogaster
Sequence 2:	XP_692110.2	Gene:	si:dkey-154p10.3 / 563659	ZFINID:	ZDB-GENE-070912-380	Length:	646	Species:	Danio rerio

Alignment Length:	293	Identity:	60/293 - (20%)
Similarity:	93/293 - (31%)	Gaps:	104/293 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   148 VERVKTNLISLLNKKYAINEDMGQEGSPPLKMQKMVGGSANRSLEESPSADLLRPRKLLQGNPVG 212
            :.|::..|.|.:.||...|..:|:|.|                                  |..|
Zfish   449 LRRMQPELWSQIRKKKVKNRAVGKEKS----------------------------------NEGG 479

  Fly   213 QSKIAPGTTQSSVQGTQTVQRKATKIYKCTSCDYKTSDMRLFNTHYETCK-QQTFQCKTCRKIFP 276
            :.::.....::|| |....:||.   :.|..||.|.|.......|....: .:.|:|..|.....
Zfish   480 KDRVKHLKAETSV-GLTVTRRKE---FCCNLCDKKFSTKLTMRRHMGIHQGDKPFKCPHCHYCTR 540

  Fly   277 HFGAMKQHMVRDHNTAMDNTCAMCHINFVNENSLRKHMETNHATNVLVTSTTTIPASAAPVAAAA 341
            ...::.||: |.|.......|..|....::.:|||:|..|:         |...|
Zfish   541 LKASLIQHL-RIHTGEKPYKCLQCSYASIDRSSLRRHSRTH---------TQEKP---------- 585

  Fly   342 AAAAAAANENLVGTSLYTCNHCQFKSTDKVVFDEHMRKHAAGKPKPFKCRLCSQRFETREAATVH 406
                            |.|.:|.:.|..|...|.|.|:|..|  :.|.|.||
Zfish   586 ----------------YCCQYCPYSSIQKKCLDLHSRRHHTG--ESFPCHLC------------- 619

  Fly   407 AKQHQTNFFKCGTCSMTFPKREMLVKHFEVHQS 439
              |:.|            |.|::||:|...|.:
Zfish   620 --QYST------------PDRQLLVRHMRKHHT 638

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pzg	NP_001262143.1	C2H2 Zn finger	241..263	CDD:275371	6/22 (27%)
		C2H2 Zn finger	268..289	CDD:275371	5/20 (25%)
		C2H2 Zn finger	297..318	CDD:275371	7/20 (35%)
		C2H2 Zn finger	360..380	CDD:275368	7/19 (37%)
		zf-H2C2_2	373..399	CDD:290200	9/25 (36%)
		zf-C2H2_8	375..443	CDD:292531	16/65 (25%)
		C2H2 Zn finger	390..410	CDD:275368	3/19 (16%)
		C2H2 Zn finger	417..437	CDD:275368	5/19 (26%)
si:dkey-154p10.3	XP_692110.2	C2H2 Zn finger	275..295	CDD:275368
		C2H2 Zn finger	303..323	CDD:275368
		C2H2 Zn finger	334..350	CDD:275368
		COG5048	<500..632	CDD:227381	43/199 (22%)
		C2H2 Zn finger	504..524	CDD:275368	6/19 (32%)
		zf-H2C2_2	517..539	CDD:290200	4/21 (19%)
		C2H2 Zn finger	532..552	CDD:275368	5/20 (25%)
		C2H2 Zn finger	560..580	CDD:275368	6/19 (32%)
		zf-H2C2_2	572..594	CDD:290200	10/56 (18%)
		C2H2 Zn finger	588..608	CDD:275368	7/19 (37%)
		C2H2 Zn finger	616..636	CDD:275368	10/46 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24403
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100