DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pzg and CG17803

DIOPT Version :9

Sequence 1:	NP_001262143.1	Gene:	pzg / 40351	FlyBaseID:	FBgn0259785	Length:	996	Species:	Drosophila melanogaster
Sequence 2:	NP_001303488.1	Gene:	CG17803 / 42141	FlyBaseID:	FBgn0038547	Length:	587	Species:	Drosophila melanogaster

Alignment Length:	358	Identity:	79/358 - (22%)
Similarity:	136/358 - (37%)	Gaps:	69/358 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   144 LENDVER---VKTN-----LISLLNKKYAINEDMGQ--EGSPPLKMQKMVGGSANRSLEESPSAD 198
            |:.|.|:   ::.|     :||:  :|....|::|:  .|:   |:.|:|.|..|...|.:|...
  Fly   234 LDRDTEKDFALEQNKSCNEIISI--RKCKTKEEIGKVDHGA---KVYKVVLGEYNSLKETAPKYS 293

  Fly   199 LLRPRKLLQGNPVGQSKIAPGTTQSSVQGTQTVQRKATKIYKCTSCDY---KTSDMRLFNTHYET 260
            |..|:|       .|.:::|  .:.:.:..:.:|.|... |.|..|.:   :.|.:::....:..
  Fly   294 LSLPKK-------PQLRVSP--EEKNRRRRERIQAKPLN-YVCDKCGHTFRQRSQLQMHLLRHNR 348

  Fly   261 CKQQTFQCKTCRKIFPHFGAMKQHMVRDHNTAMDNTCAMCHINFVNENSLRKHMETNHATNVLVT 325
            .|  .|:|..|.|.|........|:...|.......|..|:.:|.|.:|..:|....|.
  Fly   349 AK--NFECPECPKKFYDLYTRNIHVRALHKGEHPFPCNHCNESFANASSRHRHERDVHG------ 405

  Fly   326 STTTIPASAAPVAAAAAAAAAAANENLVGTSLYTCNHCQFKSTDKVVFDEHMRKHAAGKPKPFKC 390
                        |.........:.|.  |:|.:.|..|....|.|.....||..|...  :||:|
  Fly   406 ------------AGNRIRTRVKSKEE--GSSRHYCTQCTKSYTSKKGLVLHMNFHNGS--RPFQC 454

  Fly   391 RLCSQRFETREAATVHAKQHQTNFFKCGTCSMTFPKREMLVKHFEVH--QSPSASTVSP-----K 448
            ::|..:|....|...|...|.....:|..|...|..|..|.||.:||  ..|....:..     :
  Fly   455 KICQMKFADPSAMKRHQALHDKFPIRCDICLKGFLLRSQLTKHQDVHTGMHPHRCEICDVHYRHR 519

  Fly   449 QSVSQNLNT-------QKLLQETID---EALSD 471
            .:::::.||       ||.::|.::   :|..|
  Fly   520 YNLNKHKNTDLHRDNMQKAIKEEVNGLQQAFKD 552

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pzg	NP_001262143.1	C2H2 Zn finger	241..263	CDD:275371	3/24 (13%)
		C2H2 Zn finger	268..289	CDD:275371	5/20 (25%)
		C2H2 Zn finger	297..318	CDD:275371	6/20 (30%)
		C2H2 Zn finger	360..380	CDD:275368	6/19 (32%)
		zf-H2C2_2	373..399	CDD:290200	8/25 (32%)
		zf-C2H2_8	375..443	CDD:292531	21/69 (30%)
		C2H2 Zn finger	390..410	CDD:275368	5/19 (26%)
		C2H2 Zn finger	417..437	CDD:275368	7/19 (37%)
CG17803	NP_001303488.1	zf-AD	86..160	CDD:214871
		COG5048	<323..528	CDD:227381	48/229 (21%)
		zf-C2H2	324..346	CDD:278523	4/21 (19%)
		C2H2 Zn finger	326..346	CDD:275368	3/19 (16%)
		C2H2 Zn finger	354..375	CDD:275368	5/20 (25%)
		C2H2 Zn finger	383..401	CDD:275368	6/17 (35%)
		C2H2 Zn finger	426..446	CDD:275368	6/19 (32%)
		C2H2 Zn finger	454..474	CDD:275368	5/19 (26%)
		C2H2 Zn finger	481..501	CDD:275368	7/19 (37%)
		C2H2 Zn finger	509..528	CDD:275368	0/18 (0%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455483
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930