DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pzg and CG4707

DIOPT Version :9

Sequence 1:	NP_001262143.1	Gene:	pzg / 40351	FlyBaseID:	FBgn0259785	Length:	996	Species:	Drosophila melanogaster
Sequence 2:	NP_611944.1	Gene:	CG4707 / 37935	FlyBaseID:	FBgn0035036	Length:	673	Species:	Drosophila melanogaster

Alignment Length:	383	Identity:	73/383 - (19%)
Similarity:	127/383 - (33%)	Gaps:	99/383 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   129 YVCSRCTNLV-NYYD-----RLENDVERVKTNLISLLNKKYAINEDMGQEGSPPLKMQKMVGGSA 187
            :.||.|..|| |:.|     |:.:::|   :..|....:|:.:.:.:.:...........:....
  Fly   332 FPCSLCNLLVQNFADMRRHQRVSHNIE---SGYIECCGRKFHLRKALAEHVLVHKNPDHFMCSQC 393

  Fly   188 NRSLEESPSADLLRPRKLLQGNPVGQSKIAPGTTQSSVQGTQTVQRKATKIYKCTSCDYKTSDMR 252
            .|..::|.:   |...:....||  :.|..|               |..:||:|..|. |:...:
  Fly   394 GRVFQDSRA---LEVHEQTHTNP--EVKAEP---------------KEKRIYQCEKCP-KSFTTK 437

  Fly   253 LFNTHYETCK-----QQTFQCKTCRKIFPHFGAMKQHMVRDHNTAMDNTCAMCHINFVNENSLRK 312
            ....:::..|     :..:.|..|.|..|....:|:|:...|:......|..|.....::.:|:|
  Fly   438 AAMEYHDVSKHVPKSEFKYSCPECNKKIPTERKLKEHLRYMHDPEAAIICDKCGKTLRSQTNLKK 502

  Fly   313 HMETNHATNVLVTSTTTIP-ASAAPVAAAAAAAAAAANENLVGTSL------------------- 357
            |.|..|:..         | ....||..           .:.||.|
  Fly   503 HHELEHSEK---------PRPKPDPVQC-----------EICGTWLRHLSGLKQHMKTVHEPPGD 547

  Fly   358 -YTCNHCQFKSTDKVVFDEHM-RKHAAGKPKPFKCRLCSQRFETREAATVHAKQHQTN-FFKCGT 419
             :.|:.|...||:......|: ..|..  .:.|||.:|.:.|:..:....|...|... .:.|..
  Fly   548 EHRCHICNKTSTNSRALKRHIYHNHLC--ERKFKCGMCEKAFKRPQDLREHTSTHTGEVLYTCPN 610

  Fly   420 CSMTFPKREMLVKHFE-VHQ------------------SPSASTVSPKQSVSQNLNTQ 458
            |.|||.....:.||.: :|:                  |..|:|...|:..|..|..|
  Fly   611 CPMTFFSNANMYKHRQRLHRAEWEADRKKPLPPNIMKISQGATTAMKKRQTSGALFPQ 668

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pzg	NP_001262143.1	C2H2 Zn finger	241..263	CDD:275371	4/26 (15%)
		C2H2 Zn finger	268..289	CDD:275371	6/20 (30%)
		C2H2 Zn finger	297..318	CDD:275371	6/20 (30%)
		C2H2 Zn finger	360..380	CDD:275368	5/20 (25%)
		zf-H2C2_2	373..399	CDD:290200	7/26 (27%)
		zf-C2H2_8	375..443	CDD:292531	18/88 (20%)
		C2H2 Zn finger	390..410	CDD:275368	4/19 (21%)
		C2H2 Zn finger	417..437	CDD:275368	7/20 (35%)
CG4707	NP_611944.1	zf-AD	3..73	CDD:285071
		C2H2 Zn finger	334..355	CDD:275368	8/20 (40%)
		LIM	<361..407	CDD:295319	5/48 (10%)
		C2H2 Zn finger	365..382	CDD:275368	1/16 (6%)
		C2H2 Zn finger	390..410	CDD:275368	3/22 (14%)
		C2H2 Zn finger	427..443	CDD:275368	3/16 (19%)
		C2H2 Zn finger	458..476	CDD:275368	6/17 (35%)
		C2H2 Zn finger	487..507	CDD:275368	6/19 (32%)
		C2H2 Zn finger	521..540	CDD:275368	3/29 (10%)
		C2H2 Zn finger	551..572	CDD:275368	5/20 (25%)
		C2H2 Zn finger	580..600	CDD:275368	4/19 (21%)
		C2H2 Zn finger	608..629	CDD:275368	7/20 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24403
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100