DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pzg and CG1602

DIOPT Version :9

Sequence 1:	NP_001262143.1	Gene:	pzg / 40351	FlyBaseID:	FBgn0259785	Length:	996	Species:	Drosophila melanogaster
Sequence 2:	NP_610291.2	Gene:	CG1602 / 35684	FlyBaseID:	FBgn0033186	Length:	577	Species:	Drosophila melanogaster

Alignment Length:	359	Identity:	68/359 - (18%)
Similarity:	124/359 - (34%)	Gaps:	91/359 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   186 SANRSLEESPSADLLRPRKLLQGNPVGQSKIAPGTTQSSVQGTQTVQRKATK--IYKCTSCDYKT 248
            |:.:...||.:|::..|...:..:.:.:          ::|..:....|.||  ||..::.:
  Fly   295 SSRKQAYESMAAEISVPNVDINSDDIFR----------AIQNLRQWYYKNTKHAIYAGSTAE--- 346

  Fly   249 SDMRLFNTHYETCK-------QQTFQCKTCRKIFPHFGAMKQHMVRDHNTA-MDNTCAMCHINFV 305
                  ..:.|.|:       :|...|:.|.:|......::.|:.:.||.. :...|.:|..:||
  Fly   347 ------KFYLEVCRFMPAKMYKQRLVCEFCHQITSSDHVLQSHIFKAHNIGELPFKCTLCDRSFV 405

  Fly   306 NENSLRKHMETNHATNVLVTSTTTIPASAAPVAAAAAAAAAAANENLVGTSLYTCNHCQFKSTDK 370
            ....|..|::..|                                  :|.: :.|.||:......
  Fly   406 GRCELANHIQRVH----------------------------------IGKT-HKCTHCERSFAVM 435

  Fly   371 VVFDEHMRKHAAGKPKPFKCRLCSQRFETREAATVHAKQHQTNF--FKCGTCSMTFPKREMLVKH 433
            .....|:|.|..  .||:.|..|.:.|..|...|:|.....|..  |||..|...|.|:..|..|
  Fly   436 SDLQLHIRTHTG--HKPYVCEHCGKAFRLRSQMTLHVTAIHTKIRAFKCTMCPKDFVKKVDLSDH 498

  Fly   434 FEVHQSPSASTVSPKQSVSQNLNTQKLLQETIDEALSDSLPASTAAVVATTESENNIRFFSCSIC 498
            .:.|                 ||.:..:.....:..:     |..|::...:..:.::.|.|.:|
  Fly   499 IKGH-----------------LNIRDKICSVCGKGFT-----SCHALIRHRQIHSEVKKFVCKLC 541

  Fly   499 SLTFIQETYYNHHME-THRRDKKATSAGATALNS 531
            ...|.|....|.||: ||...:..:..|..|:::
  Fly   542 DSRFSQFVGLNTHMKRTHNILRNNSQKGKDAVDA 575

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pzg	NP_001262143.1	C2H2 Zn finger	241..263	CDD:275371	2/28 (7%)
		C2H2 Zn finger	268..289	CDD:275371	4/20 (20%)
		C2H2 Zn finger	297..318	CDD:275371	6/20 (30%)
		C2H2 Zn finger	360..380	CDD:275368	5/19 (26%)
		zf-H2C2_2	373..399	CDD:290200	8/25 (32%)
		zf-C2H2_8	375..443	CDD:292531	21/69 (30%)
		C2H2 Zn finger	390..410	CDD:275368	6/19 (32%)
		C2H2 Zn finger	417..437	CDD:275368	6/19 (32%)
CG1602	NP_610291.2	GT1	157..244	CDD:304916
		MADF_DNA_bdg	273..356	CDD:287510	13/79 (16%)
		C2H2 Zn finger	367..388	CDD:275368	4/20 (20%)
		C2H2 Zn finger	397..418	CDD:275368	6/20 (30%)
		COG5048	<423..554	CDD:227381	34/154 (22%)
		C2H2 Zn finger	425..445	CDD:275368	5/19 (26%)
		zf-H2C2_2	437..460	CDD:290200	7/24 (29%)
		C2H2 Zn finger	453..470	CDD:275368	5/16 (31%)
		C2H2 Zn finger	482..502	CDD:275368	6/19 (32%)
		C2H2 Zn finger	510..530	CDD:275368	2/24 (8%)
		C2H2 Zn finger	538..559	CDD:275368	7/20 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440014
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930