DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment pzg and CG2129

DIOPT Version :9

Sequence 1:	NP_001262143.1	Gene:	pzg / 40351	FlyBaseID:	FBgn0259785	Length:	996	Species:	Drosophila melanogaster
Sequence 2:	NP_572449.1	Gene:	CG2129 / 31741	FlyBaseID:	FBgn0030008	Length:	465	Species:	Drosophila melanogaster

Alignment Length:	416	Identity:	84/416 - (20%)
Similarity:	133/416 - (31%)	Gaps:	113/416 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   145 ENDVERVKTNLI------SL----LNKKYAINEDMGQEGSPPLKMQKMVGGSANRSLEESPSADL 199
            |::.||...::|      ||    |.:..|:..|..:|.|.    |:..|...:...|...||.:
  Fly   119 EDEDERPGRSIIKWQDHQSLTSESLRQVRALKVDYKEEDSE----QEECGMELDLDSEGRHSAKI 179

  Fly   200 ----------LRPRKLLQGNPVGQSK--IAPGTTQSSVQ---GTQTVQRKATKIYKCTSCDYKTS 249
                      .:.||:|:.:.:.|.|  ::|........   ......:.|.:.|||..|.
  Fly   180 PHSCPHCTKVYQSRKVLERHIMRQHKDTLSPDVDSEDADYEPPKDAPVKSAAQEYKCEHCG---- 240

  Fly   250 DMRLFNTHY-------------ETCKQQTFQCKTCRKIFPHFGAMKQHMVRDHNTAMDNTCAMCH 301
              ::::..|             |......|.|..|....|....:.:|||:.|..|   .|.:|.
  Fly   241 --KIYHGKYSLRQHLKRDHDNGEEGGSAIFTCLECEAQLPRLRLLDEHMVQAHGGA---ACVVCG 300

  Fly   302 INFVNENSLRKHMETNHATNVLVTSTTTIPASAAPVAAAAAAAAAAANENLVGTSL--YTCNHCQ 364
            ..:...:.|::| :..|      ||...:|.................|...|.|..  :.|..|.
  Fly   301 RRYKTRHELKRH-QLKH------TSERNVPCPHPGCGKRFFTIRHMRNHGKVHTEQKNFVCESCG 358

  Fly   365 FKSTDKVVFDEHMRKHAAGKPKPFKCRLCSQRFETREAATVHAKQHQTNF-FKCGTCSMTFPKRE 428
            :...:|.....|:|.|..  .:||.|::|.:||.:......|...|.|.. ..|..|..||.:::
  Fly   359 YSCRNKETLRVHIRSHTG--ERPFGCQVCDKRFPSHSGLREHMAMHSTERPHVCSVCGATFSRQK 421

  Fly   429 MLVKHFEVHQSPSASTVSPKQSVSQNLNTQKLLQETIDEALSDSLPASTAAVVATTESENNIRFF 493
            .|..|..:|    |.|   ||                                           |
  Fly   422 GLYHHKFLH----ADT---KQ-------------------------------------------F 436

  Fly   494 SCSICSLTFIQETYYNHHMETHRRDK 519
            .|.:|...:.|......||..||.|:
  Fly   437 VCKLCGNAYAQAAGLAGHMRKHRNDE 462

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pzg	NP_001262143.1	C2H2 Zn finger	241..263	CDD:275371	4/34 (12%)
		C2H2 Zn finger	268..289	CDD:275371	6/20 (30%)
		C2H2 Zn finger	297..318	CDD:275371	4/20 (20%)
		C2H2 Zn finger	360..380	CDD:275368	5/19 (26%)
		zf-H2C2_2	373..399	CDD:290200	9/25 (36%)
		zf-C2H2_8	375..443	CDD:292531	19/68 (28%)
		C2H2 Zn finger	390..410	CDD:275368	5/19 (26%)
		C2H2 Zn finger	417..437	CDD:275368	6/19 (32%)
CG2129	NP_572449.1	C2H2 Zn finger	296..316	CDD:275370	4/20 (20%)
		zf-C2H2_8	323..411	CDD:292531	19/89 (21%)
		C2H2 Zn finger	327..346	CDD:275368	1/18 (6%)
		C2H2 Zn finger	354..374	CDD:275368	5/19 (26%)
		zf-H2C2_2	367..389	CDD:290200	7/23 (30%)
		C2H2 Zn finger	382..402	CDD:275368	5/19 (26%)
		zf-H2C2_2	395..419	CDD:290200	7/23 (30%)
		C2H2 Zn finger	410..430	CDD:275368	6/19 (32%)
		C2H2 Zn finger	438..458	CDD:275368	5/19 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440017
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930