DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pzg and ZNF513

DIOPT Version :9

Sequence 1:	NP_001262143.1	Gene:	pzg / 40351	FlyBaseID:	FBgn0259785	Length:	996	Species:	Drosophila melanogaster
Sequence 2:	NP_653232.3	Gene:	ZNF513 / 130557	HGNCID:	26498	Length:	541	Species:	Homo sapiens

Alignment Length:	169	Identity:	40/169 - (23%)
Similarity:	63/169 - (37%)	Gaps:	34/169 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   297 CAMCHINFVNENSLRKHMETNHATNVLVTSTTTIPASAAPVAAAAAAAAAAANENL-------VG 354
            |::|.......|.|.:||:|:              :...|...|....|:|..:||       .|
Human   362 CSLCPFATHYPNHLARHMKTH--------------SGEKPFRCARCPYASAHLDNLKRHQRVHTG 412

  Fly   355 TSLYTCNHCQFKSTDKVVFDEHMRKHAAGKPKPFKCRLCSQRFETREAATVHAKQHQTNF----- 414
            ...|.|..|.:...:......|.|.|:.  .|||:|.||:....    .:::.|:|....
Human   413 EKPYKCPLCPYACGNLANLKRHGRIHSG--DKPFRCSLCNYSCN----QSMNLKRHMLRHTGEKP 471

  Fly   415 FKCGTCSMTFPKREMLVKHFEVHQSPSASTVSPKQSVSQ 453
            |:|.||:.|....:...:|.:||....|.  .|..|.|:
Human   472 FRCATCAYTTGHWDNYKRHQKVHGHGGAG--GPGLSASE 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pzg	NP_001262143.1	C2H2 Zn finger	241..263	CDD:275371
		C2H2 Zn finger	268..289	CDD:275371
		C2H2 Zn finger	297..318	CDD:275371	7/20 (35%)
		C2H2 Zn finger	360..380	CDD:275368	4/19 (21%)
		zf-H2C2_2	373..399	CDD:290200	9/25 (36%)
		zf-C2H2_8	375..443	CDD:292531	19/72 (26%)
		C2H2 Zn finger	390..410	CDD:275368	4/19 (21%)
		C2H2 Zn finger	417..437	CDD:275368	5/19 (26%)
ZNF513	NP_653232.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..118
		C2H2 Zn finger	152..172	CDD:275368
		COG5048	176..>228	CDD:227381
		C2H2 Zn finger	180..200	CDD:275368
		zf-H2C2_2	192..217	CDD:316026
		C2H2 Zn finger	208..228	CDD:275368
		C2H2 Zn finger	362..382	CDD:275368	6/19 (32%)
		COG5048	<372..>450	CDD:227381	23/93 (25%)
		C2H2 Zn finger	390..410	CDD:275368	5/19 (26%)
		COG5048	414..>487	CDD:227381	19/78 (24%)
		C2H2 Zn finger	418..438	CDD:275368	4/19 (21%)
		C2H2 Zn finger	446..466	CDD:275368	5/23 (22%)
		C2H2 Zn finger	474..493	CDD:275368	5/18 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	492..541		6/19 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24403
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.100