DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pzg and LOC108182171

DIOPT Version :9

Sequence 1:	NP_001262143.1	Gene:	pzg / 40351	FlyBaseID:	FBgn0259785	Length:	996	Species:	Drosophila melanogaster
Sequence 2:	XP_017209855.2	Gene:	LOC108182171 / 108182171	-ID:	-	Length:	697	Species:	Danio rerio

Alignment Length:	567	Identity:	121/567 - (21%)
Similarity:	180/567 - (31%)	Gaps:	175/567 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 CYICDDRCEPQTSLTDMCTTHTSTKFPNKLAQLVGEGFLVIVCGEDYVCSRCTNLVNYYDRLEND 147
            |..|......:::|......||..|                    .|.|.:|.....|....:|.
Zfish    84 CTWCRKSFSKKSNLDIHMRVHTKEK--------------------PYTCKQCGKRFGYIQGFKNH 128

  Fly   148 VERVKTNLISLLNKKYAINEDMGQEGSPPLKMQKMVGGSANRSLEESPSADLLRPRKLLQGNPVG 212
            : |:.|                   |..|...|:     ..:|...:             ||...
Zfish   129 M-RIHT-------------------GERPYTCQQ-----CGKSFYHA-------------GNFAA 155

  Fly   213 QSKIAPGTTQSSVQ---------GTQTVQRK---ATKIYKCTSC--DYKTS-----DMRLFNTHY 258
            ..||..|..:.:.|         |...|..:   ..|.|.|:.|  .:|.:     .||   ||.
Zfish   156 HQKIHTGERKYTCQHCGKSFSKTGNLAVHMRIHTGEKPYSCSQCGKSFKQNVTLKIHMR---THN 217

  Fly   259 E----TCKQ---------------------QTFQCKTCRKIFPHFGAMKQHMVRDHNTAMDNTCA 298
            |    ||.|                     :.:.|..|.|.||:.|::..||: .|......|||
Zfish   218 EERIFTCTQCGKSISQKHYLDIHMRIHTGEKPYTCTECGKSFPYKGSLNHHMI-SHTGEKPFTCA 281

  Fly   299 MCHINFVNENSLRKHMETNHATNVLVTSTTTIPASAAPVAAAAAAAAAAANENL-----VGTSLY 358
            .|..:|..:::|.:||.. |....|.|.|           ....:.:.:||.|:     .|...:
Zfish   282 QCGKSFTTKSNLNQHMRI-HTGEKLFTCT-----------QCGKSFSNSANLNIHMRIHTGEKPF 334

  Fly   359 TCNHCQFKSTDKVVFDEHMRKHAAGKPKPFKCRLCSQRFETREAATVHAKQHQ-TNFFKCGTCSM 422
            ||..|....::....::|||.|..  .|||.|..|.:.|.......:|.:.|. ...|.|..|..
Zfish   335 TCTQCGKSFSNSANLNQHMRIHTG--EKPFTCTQCGKSFSQSSNLNLHMRIHTGEKPFTCSQCGK 397

  Fly   423 TFPKREMLVKHFEVH--QSPSASTVSPKQ-SVSQNLNTQKLLQETIDEALSDSLPASTAAVVATT 484
            :|.:...|..|..:|  :.|...|...|. |.|..||..                         .
Zfish   398 SFSQSSSLNLHMRIHTGEKPFTCTQCGKSFSQSSILNIH-------------------------M 437

  Fly   485 ESENNIRFFSCSICSLTFIQETYYNHHMETHRRDK--KATSAGATALNSAATAL-----LSDEPG 542
            .:....:.|:|..|..:|.|.||.|.||..|..:.  ..|..|.:..|||...|     ..::|.
Zfish   438 RNHTGEKPFTCLQCGKSFSQSTYLNQHMRIHTGENLFTCTHCGKSFSNSANLNLHMRIHTGEKPF 502

  Fly   543 EAT--GKAGDESGEQNAEADIESLFEKLHSDKNESGEAPKPGSKGGE 587
            ..|  ||:..:|...|       :..::|     :||.|...|:.|:
Zfish   503 TCTQCGKSFSQSSNLN-------IHMRIH-----TGEKPFTCSQCGK 537

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pzg	NP_001262143.1	C2H2 Zn finger	241..263	CDD:275371	10/32 (31%)
		C2H2 Zn finger	268..289	CDD:275371	8/20 (40%)
		C2H2 Zn finger	297..318	CDD:275371	7/20 (35%)
		C2H2 Zn finger	360..380	CDD:275368	5/19 (26%)
		zf-H2C2_2	373..399	CDD:290200	10/25 (40%)
		zf-C2H2_8	375..443	CDD:292531	20/70 (29%)
		C2H2 Zn finger	390..410	CDD:275368	4/19 (21%)
		C2H2 Zn finger	417..437	CDD:275368	5/19 (26%)
LOC108182171	XP_017209855.2	C2H2 Zn finger	84..104	CDD:275368	3/19 (16%)
		zf-H2C2_2	96..121	CDD:316026	7/44 (16%)
		C2H2 Zn finger	112..132	CDD:275368	5/20 (25%)
		zf-H2C2_2	125..149	CDD:316026	7/48 (15%)
		C2H2 Zn finger	140..160	CDD:275368	5/37 (14%)
		C2H2 Zn finger	168..188	CDD:275368	3/19 (16%)
		zf-H2C2_2	180..205	CDD:316026	5/24 (21%)
		C2H2 Zn finger	196..216	CDD:275368	5/22 (23%)
		C2H2 Zn finger	224..244	CDD:275368	2/19 (11%)
		zf-H2C2_2	236..259	CDD:316026	3/22 (14%)
		C2H2 Zn finger	252..272	CDD:275368	8/20 (40%)
		zf-H2C2_2	264..289	CDD:316026	8/25 (32%)
		C2H2 Zn finger	280..300	CDD:275368	7/20 (35%)
		zf-H2C2_2	292..317	CDD:316026	7/36 (19%)
		COG5048	308..688	CDD:227381	63/280 (23%)
		C2H2 Zn finger	308..328	CDD:275368	4/30 (13%)
		C2H2 Zn finger	336..356	CDD:275368	5/19 (26%)
		C2H2 Zn finger	364..384	CDD:275368	4/19 (21%)
		C2H2 Zn finger	392..412	CDD:275368	5/19 (26%)
		C2H2 Zn finger	420..440	CDD:275368	6/44 (14%)
		C2H2 Zn finger	448..468	CDD:275368	9/19 (47%)
		C2H2 Zn finger	476..496	CDD:275368	6/19 (32%)
		C2H2 Zn finger	504..524	CDD:275368	5/26 (19%)
		C2H2 Zn finger	532..552	CDD:275368	2/6 (33%)
		C2H2 Zn finger	560..580	CDD:275368
		C2H2 Zn finger	588..608	CDD:275368
		C2H2 Zn finger	616..636	CDD:275368
		C2H2 Zn finger	644..664	CDD:275368
		C2H2 Zn finger	672..692	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910