DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pzg and LOC100537431

DIOPT Version :9

Sequence 1:	NP_001262143.1	Gene:	pzg / 40351	FlyBaseID:	FBgn0259785	Length:	996	Species:	Drosophila melanogaster
Sequence 2:	XP_009301501.1	Gene:	LOC100537431 / 100537431	-ID:	-	Length:	434	Species:	Danio rerio

Alignment Length:	486	Identity:	104/486 - (21%)
Similarity:	159/486 - (32%)	Gaps:	132/486 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   145 ENDVERVKTNLISLLNKKYAINEDMGQEGSPPLKMQKMVGGSANRSLEESP-----SADLLRPRK 204
            :.|::. :|:|:.|..:.:..|| |.:      |:|::       :.:|.|     ::...||||
Zfish    21 QEDLQE-QTDLMVLKEEAHEQNE-MEE------KLQEI-------TTDEKPTLTKKTSSRGRPRK 70

  Fly   205 LLQGNPVGQSKIAPGTTQSSVQGTQTVQRKATKIYKCTSCDYKTSDMRLFNTHYET-CKQQTFQC 268
            .......|..:.....:|.|.....|.:    |.|.|..|......::.|..|... ..::.|.|
Zfish    71 SKSACNFGSKQSRKSFSQKSNLDVHTRE----KPYTCEQCGKSFGHIQGFENHMRIHTGEKPFSC 131

  Fly   269 KTCRKIFPHFGAMKQHMVRDHNTAMDNTCAMCHINFVNENSLRKHMETNHATNVLVTSTTTIPAS 333
            |.|.|.|.....:..|| |.|......||..|..:|..:.....||..:
Zfish   132 KQCGKSFTQKANLDVHM-RVHTKERPYTCEQCGKSFTYKQGFTTHMRIH---------------- 179

  Fly   334 AAPVAAAAAAAAAAANENLVGTSLYTCNHCQFKSTDKVVFDEHMRKHAAGKP------------- 385
                               .|...|||..|:........|..|||.|...:|
Zfish   180 -------------------TGERPYTCQQCEKSFYHPGNFAVHMRIHTGERPYTCQQCGKSFYQS 225

  Fly   386 -------------KPFKCRLCSQRFETREAATVHAKQHQ-TNFFKCGTCSMTFPKREMLVKHFEV 436
                         :|:.|..|.:.|:......||.:.|. ...|.|..|...|.::..|..|..:
Zfish   226 GNFAAHMRIHTGERPYSCIQCGKSFKQNCTLEVHMRTHTGDRSFMCTHCGKCFSQKHDLNIHMRI 290

  Fly   437 H--QSPSASTVSPKQSVSQNLNTQKLLQETIDEALSDSLPASTAAVVATTESENNIRFFSCSICS 499
            |  :.|...|...|:.      |||   .::|..:|          :.|.|..     :.|:.|.
Zfish   291 HTGKKPHTCTQCGKRF------TQK---TSLDNHMS----------IHTGEKP-----YRCTECG 331

  Fly   500 LTFIQETYYNHHMETHRRDK--KATSAGATALNSAATALLSDEPGEATGKAG------DESGEQN 556
            .||..::...|||.||..:|  ..|..|......|:...|.|      |..|      |:..:..
Zfish   332 KTFPHKSSLKHHMRTHTGEKPFACTQCGTRFTTKASLKNLMD------GHTGTIVLTCDQCEKSL 390

  Fly   557 AEADIESLFEKLHSDKNESGEAPKPGSKGGE 587
            ...|  |:  :.|..|..|||.|...|:.|:
Zfish   391 TRKD--SI--RKHIRKINSGEDPFRCSECGK 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pzg	NP_001262143.1	C2H2 Zn finger	241..263	CDD:275371	4/22 (18%)
		C2H2 Zn finger	268..289	CDD:275371	8/20 (40%)
		C2H2 Zn finger	297..318	CDD:275371	5/20 (25%)
		C2H2 Zn finger	360..380	CDD:275368	6/19 (32%)
		zf-H2C2_2	373..399	CDD:290200	10/51 (20%)
		zf-C2H2_8	375..443	CDD:292531	20/96 (21%)
		C2H2 Zn finger	390..410	CDD:275368	5/19 (26%)
		C2H2 Zn finger	417..437	CDD:275368	5/19 (26%)
LOC100537431	XP_009301501.1	COG5048	73..433	CDD:227381	89/419 (21%)
		C2H2 Zn finger	103..123	CDD:275368	4/19 (21%)
		zf-H2C2_2	116..140	CDD:290200	8/23 (35%)
		C2H2 Zn finger	131..151	CDD:275368	8/20 (40%)
		zf-H2C2_2	143..168	CDD:290200	8/25 (32%)
		C2H2 Zn finger	159..179	CDD:275368	5/19 (26%)
		zf-H2C2_2	174..194	CDD:290200	7/54 (13%)
		C2H2 Zn finger	187..207	CDD:275368	6/19 (32%)
		zf-H2C2_2	199..222	CDD:290200	6/22 (27%)
		C2H2 Zn finger	215..235	CDD:275368	0/19 (0%)
		zf-H2C2_2	227..252	CDD:290200	4/24 (17%)
		C2H2 Zn finger	243..263	CDD:275368	5/19 (26%)
		zf-H2C2_2	256..280	CDD:290200	7/23 (30%)
		C2H2 Zn finger	271..291	CDD:275368	5/19 (26%)
		zf-H2C2_2	283..308	CDD:290200	6/30 (20%)
		C2H2 Zn finger	299..319	CDD:275368	7/38 (18%)
		zf-H2C2_2	311..334	CDD:290200	6/37 (16%)
		zf-C2H2	325..347	CDD:278523	7/21 (33%)
		C2H2 Zn finger	327..347	CDD:275368	7/19 (37%)
		zf-H2C2_2	339..364	CDD:290200	8/24 (33%)
		C2H2 Zn finger	383..404	CDD:275368	5/24 (21%)
		C2H2 Zn finger	412..432	CDD:275368	2/6 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910