Protein Alignment AcCoAS and acss2l

DIOPT Version :9

• Sequence 1: NP_001014599.2
• Gene: AcCoAS / 40348
• FlyBaseID: FBgn0012034
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_001264046.2
• Gene: acss2l / 560020
• ZFINID: ZDB-GENE-130530-723
• Length: 684
• Species: Danio rerio
• Alignment Length: 665
• Identity: 403/665 - (60%)
• Similarity: 512/665 - (76%)
• Gaps: 7/665 - (1%)

  Fly     4 EKSIYDPNPAISQNAYISSFEEYQKFYQESLDNPAEFWSRVAKQFHWETPADQDKFLKYNFNISK 68
            |:.||.|...|..:|::..|:.|...|::|::.|.|||..||::|.|:.| ...:.|:|||:::|
Zfish    19 EEKIYHPPDGIFTDAHVPDFDAYLALYKKSIEEPEEFWGDVAQEFFWKKP-PSGQMLQYNFDVTK 82

  Fly    69 GPISIKWMEGASTNLCYNLLDRNV--RNGLGDQIAYYWEGNHPDDYSRGLTYRKLLEEVCRFANV 131
            |.:.||:|:||.||:|||:|||||  || |||::||||.||.||.:.. :||.:||..|||.||.
Zfish    83 GSVFIKFMDGAKTNICYNVLDRNVHERN-LGDKVAYYWVGNSPDHHLT-ITYNQLLRNVCRCANA 145

  Fly   132 LKDHGIRKGDRVSIYMPMILELPIAMLACARIGAVHSIVFAGFSPDSLAERMFDCKAKLLITADG 196
            ||..|::|||||:||:|||.||...|||||||||||||||||||.:||.||:.|.:..:|:||||
Zfish   146 LKLLGVKKGDRVAIYLPMIPELVYTMLACARIGAVHSIVFAGFSSESLCERIMDAQCNILVTADG 210

  Fly   197 AWRGEKPLYLKALCDTALEKVEE-MGHSVEKCIVVSHLKRVTPCQPDHVEEEIPWTDDRDYWWHE 260
            .:||:|.:.||.:...||::.:| ...||:||:||.|...:|...... ..:.||.:..|.||.:
Zfish   211 VYRGDKLINLKKIASEALDRCKESSASSVQKCVVVKHPAFITSSDASS-SLQTPWDELCDIWWDD 274

  Fly   261 EMEDKEPACYPEWMDAEDPLFMLYTSGSTGKPKGVLHTTAGYLLYAATTFKIVFDYKPGDIYWCT 325
            .|:.....|.|||||:|||||:|||||||||||||:||..||:||.:.|||.||||...|:||||
Zfish   275 LMDGVSDECEPEWMDSEDPLFILYTSGSTGKPKGVVHTVTGYMLYTSLTFKYVFDYHHDDVYWCT 339

  Fly   326 GDVGWITGHTYVVYGPLANGATSVIFEGTPFFPGNDRYWSVIDKYKVTQFYTAPTAIRALMKFGE 390
            .|:||||||:|:.|||||||||||:|||.|..|...|.|.:|:||.|::|||||||||.|||:|:
Zfish   340 ADIGWITGHSYITYGPLANGATSVLFEGVPVHPHVGRLWEIIEKYGVSKFYTAPTAIRLLMKYGK 404

  Fly   391 GPVLKHNLSGLKVLGSVGEPINPEAWLWYYKYIGKEQCSIVDTFWQTETGGHVITPLPGATPMKP 455
            .|:.:::||.|:|||:||||||||||||||..:|:::|.::||||||||||||:||||.|||:||
Zfish   405 EPLQRYDLSSLRVLGTVGEPINPEAWLWYYDVVGQQRCPVIDTFWQTETGGHVLTPLPAATPLKP 469

  Fly   456 GSASFPFFGVKPTLLDECGIEIKGEGEGYLVFSQPWPGMMRTLYNNHERFEDTYFSKFPGYYCTG 520
            |||:.|||||:|.:|:|.|.|::||.||||||.|||||:||.::.|.||||.|||.||||:|.||
Zfish   470 GSATCPFFGVQPAILNEHGEELEGEAEGYLVFRQPWPGIMRGVFGNQERFESTYFRKFPGFYVTG 534

  Fly   521 DGARRDADGYLWITGRVDDMLNVSGHLMSTAEVESVLTEHPRVAESAVVSRPHPVKGECLYCFIT 585
            ||.|||.|||.|||||:||||||||||:|||||||.|:|||.|||:||||.||.|||||||||||
Zfish   535 DGCRRDKDGYYWITGRIDDMLNVSGHLLSTAEVESALSEHPSVAEAAVVSCPHAVKGECLYCFIT 599

  Fly   586 PNENEVFDQKLISDLKKMVRERIGPFAMPDVIQNAPGLPKTRSGKIMRRVLRKIAVNDRNVGDTS 650
            ..:.:.|::.|:.:||:.|||:|||.|.||.|||||||||||||||||||||:||.|::.:||.|
Zfish   600 LKDQQEFNRTLMDELKRKVREKIGPIATPDFIQNAPGLPKTRSGKIMRRVLRQIARNEKELGDLS 664

  Fly   651 TLADEQIVEQLFANR 665
            ||||.::||.||:.|
Zfish   665 TLADPKVVEVLFSQR 679

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AcCoAS	NP_001014599.2	PRK00174	7..665	CDD:234677	401/660 (61%)
		ACS	30..654	CDD:213313	388/626 (62%)
acss2l	NP_001264046.2	ACS	45..668	CDD:213313	388/626 (62%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	117	1.000	Domainoid score	I5895
eggNOG	1	0.900	-	-		E1_COG0365
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	883	1.000	Inparanoid score	I376
OMA	1	1.010	-	-		QHG61013
OrthoDB	1	1.010	-	-		D148550at33208
OrthoFinder	1	1.000	-	-		FOG0001357
OrthoInspector	1	1.000	-	-		otm24209
orthoMCL	1	0.900	-	-		OOG6_100430
Panther	1	1.100	-	-	O	PTHR24095
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X954
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	12	11.840