Protein Alignment AcCoAS and CG6432

DIOPT Version :9

• Sequence 1: NP_001014599.2
• Gene: AcCoAS / 40348
• FlyBaseID: FBgn0012034
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_001287502.1
• Gene: CG6432 / 42901
• FlyBaseID: FBgn0039184
• Length: 674
• Species: Drosophila melanogaster
• Alignment Length: 707
• Identity: 237/707 - (33%)
• Similarity: 351/707 - (49%)
• Gaps: 91/707 - (12%)

  Fly     1 MPAEKSIYDPNPAISQNAYISSFEEYQKFYQESLDNPAEFWSRVAKQFHWETPADQDKFLKYNFN 65
            ||.|  .:||              .|.|.|::|:.|||.||........|:.|  .:|.|.
  Fly    19 MPVE--AHDP--------------LYLKAYRQSVQNPAAFWEEQGNLLDWDRP--WEKVLD---- 61

  Fly    66 ISKGPISIKWMEGASTNLCYNLLDRNVRNGLGDQIAYYWEGNHPDDYS---RGLTYRKLLEEVCR 127
             :..|...||..|...|.|||.:||::..|.|..:|..    |....:   |.:||::|.:::..
  Fly    62 -NSNPPFTKWYVGGYLNACYNSIDRHILAGRGSNVALI----HDSPLTGTLRRVTYQELYDQIVL 121

  Fly   128 FANVLKDHGIRKGDRVSIYMPMILELPIAMLACARIGAVHSIVFAGFSPDSLAERMFDCKAKLLI 192
            .|..|...|:.|||||.||||:|.|..|||||..|:||:||:||.||:...|..|:...:.||:|
  Fly   122 LAGGLAKLGVVKGDRVVIYMPLIPETIIAMLAIVRLGAIHSVVFGGFAARELCSRIEHVEPKLVI 186

  Fly   193 TAD-GAWRGEKPLYLKALCDTALEKVEEMGHSVEKCIVVSHLKRVTPCQ------PDHVEEEIPW 250
            .:: |...|:...||..|            ||     .:| :.|..|.|      .|:|..:...
  Fly   187 ASNVGVEPGKVVPYLDIL------------HS-----AIS-MSRWRPPQRNIIFRRDNVSPDTTK 233

  Fly   251 TDD-RDYWWHEEM---EDKEP-ACYPEWMDAEDPLFMLYTSGSTGKPKGVLHTTAGYLLYAATTF 310
            .|. .|..|.:.:   |.:.| ||.|  ::|.|||::|||||:|.||||||.|..|:|:....|.
  Fly   234 LDPLTDVLWSDILKMAEGERPIACVP--IEANDPLYILYTSGTTDKPKGVLRTIGGHLVALVYTL 296

  Fly   311 KIVFDYKPGDIYWCTGDVGWITGHTYVVYGPLANGATSVIFEGTP-FFPGNDRYWSVIDKYKVTQ 374
            :.::...||..:|...|:||:.||:|:.||||..|||||::||.| ..|...:|:.:||:|:|..
  Fly   297 RTLYGINPGHTWWAASDMGWVVGHSYICYGPLCLGATSVMYEGKPDRTPDPGQYFRIIDQYQVRS 361

  Fly   375 FYTAPTAIRAL------MKFGEGPVLKHNLSGLKVLGSVGEPINPEAWLWYYKYIGKEQCSIVDT 433
            .::.||:.|.:      :.:|.    ::::..|:.:...||..:.|...|..|..   :..:::.
  Fly   362 IFSVPTSFRVIRRADPDISYGR----QYSMKSLRAIFIAGEHCDYETKSWIEKTF---KVPVLNH 419

  Fly   434 FWQTETGGHV-ITPLPGATPMKPG--SASFPFFGVKPTLLDECGIEIKGEGEGYLVFSQPW-PGM 494
            :||||||..| .|.|.....:.|.  |...|..|....:|...|.|.:....|.:....|. ||.
  Fly   420 WWQTETGSAVTATCLGFQQNLSPPTYSTGLPLMGYDVKILKADGSEAQTSELGRIALKLPLPPGN 484

  Fly   495 MRTLYNNHERFEDTYFSKFPGYYCTGDGARRDADGYLWITGRVDDMLNVSGHLMSTAEVESVLTE 559
            |.|||.|.|.|...||.||||||.|.|...:|..||:::|.|.||::||:||.:||:.:|..:..
  Fly   485 MATLYKNEELFRTLYFQKFPGYYDTMDAGYKDERGYIFVTARDDDVINVAGHRLSTSSLEDAVLR 549

  Fly   560 HPRVAESAVVSRPHPVKGECLYCFITPNEN-EVFDQKLISDLKKMVRERIGPFAMPDVIQNAPGL 623
            ||.|.:.||...|...||:...|...|.|| :..|.||.:::.|::|:.:||.|...::.:...|
  Fly   550 HPDVVDVAVFGVPEATKGQVPLCLYIPVENCKKTDAKLSTEIIKLIRDVVGPIAAFRLVTSVNNL 614

  Fly   624 PKTRSGKIMRRVLRKIAVNDR-----NVGDTSTLAD-----EQIVEQLFANRPVEAK 670
            |:|||||.||:.:...|.|:|     .:.|.|...:     .|:...:.|..|:.||
  Fly   615 PRTRSGKTMRKAMADFARNERVVLPATIDDASVFIEIRRALNQLGYAMTAPDPIVAK 671

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AcCoAS	NP_001014599.2	PRK00174	7..665	CDD:234677	231/694 (33%)
		ACS	30..654	CDD:213313	225/655 (34%)
CG6432	NP_001287502.1	prpE	28..657	CDD:182517	227/666 (34%)
		PrpE	37..651	CDD:213314	223/651 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456987
Domainoid	1	1.000	48	1.000	Domainoid score	I3474
eggNOG	1	0.900	-	-		E1_COG0365
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D148550at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.750