Protein Alignment AcCoAS and Acsm1

DIOPT Version :9

• Sequence 1: NP_001014599.2
• Gene: AcCoAS / 40348
• FlyBaseID: FBgn0012034
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_001101972.2
• Gene: Acsm1 / 361638
• RGDID: 1306813
• Length: 577
• Species: Rattus norvegicus
• Alignment Length: 634
• Identity: 175/634 - (27%)
• Similarity: 269/634 - (42%)
• Gaps: 120/634 - (18%)

  Fly    52 TPADQDKFLKYNFNISKGPISIKWM---EGAST----------NLCYNLLD------RNVRNGLG 97
            ||....||| :.|::.: |...:|:   :||..          |...::||      ...:.|.|
  Rat     9 TPLGICKFL-HRFSLHR-PQLHRWLISGDGAQRWNDYDSPEEFNFASHVLDYWAQMEGEGKRGPG 71

  Fly    98 DQIAYYWEGNHPDDYSRGLTYRKLLEEVCRFANVLKDH-GIRKGDRVSIYMPMILELPIAMLACA 161
            .  |.:|..:..|:..  .::|:|.:...|.|||.:.. |::.|||:::.:|.:.|..:..:.|.
  Rat    72 P--ALWWVNDQGDEIK--WSFRELRDLSRRAANVFEQTCGLQHGDRLALILPRVPEWWLVTVGCI 132

  Fly   162 RIGAVHSIVFAGFSPDSLAERMFDCKAKLLITADGAWRGEKPLYLKALCDTALEKVEEMGHSVEK 226
            |.|.:.....|......:..|:...:||.::|.|..                   |.|:.....:
  Rat   133 RTGVIFIPGTAQMKAKDILYRIQMSQAKAIVTTDSL-------------------VPEVESVASE 178

  Fly   227 C------IVVSHLKRVTPCQPDHVEEEIPWTDDRDYWWHEEMEDKEP--ACYPEWMDAEDPLFML 283
            |      ||||          ||..|  .|.:.|..     :....|  .|....|  :||:.:.
  Rat   179 CPGLKTKIVVS----------DHNHE--GWLNFRTL-----LRSASPDHTCVKSKM--KDPMVIF 224

  Fly   284 YTSGSTGKPKGVLHTTAGYLLYAATTFKIVFDYKPGDIYWCTGDVGWITGHTYVVYGPLANGATS 348
            :|||:||.||...|........:..:.:.....|..|:.||..|.|||......:..|...|||.
  Rat   225 FTSGTTGYPKMAKHNQGLAFRSSVPSCRKFLKLKTSDVIWCMSDPGWILATVGCLLEPWTAGATV 289

  Fly   349 VIFEGTPFFPGNDRYWSVI----DKYKVTQFYTAPTAIRAL-------MKFGEGPVLKHNLSGLK 402
            .:.....|.|      .||    .||.:||...||...|.:       ::|   |.|:|..:|
  Rat   290 FVHNLPQFDP------KVIVETLFKYPITQCLAAPAVYRMVLQKNISNLRF---PTLEHCATG-- 343

  Fly   403 VLGSVGEPINPEAWLWYYKYIGKEQCSIVDTFWQTETGGHVITPLPGATPMKPGS---ASFPFFG 464
                 ||.:.||.   |.::..:...||.:.:.|:|||  :...:.....:|.||   |..||
  Rat   344 -----GESLLPEE---YEQWKQRTGLSIHEVYGQSETG--ITCAIFREMKVKRGSIGKAILPF-- 396

  Fly   465 VKPTLLDECGIEIKGEGEGYLVF----SQPWPGMMRTLYNNHERFEDTYFSKFPGYYCTGDGARR 525
             ...::||.|..:....|||:..    ::|. |:.....|:.|:..:.....|   |.:||.|..
  Rat   397 -DIQIIDEKGNILPPNTEGYIGIRIKPTRPL-GLFVGYENSPEKTSEVECGDF---YNSGDRATI 456

  Fly   526 DADGYLWITGRVDDMLNVSGHLMSTAEVESVLTEHPRVAESAVVSRPHPVKGECLYCFITPN-EN 589
            |.|||:|..||.||::|.||:.:...|||:.|.|||.|:||||||.|...:||.:..||..| |.
  Rat   457 DEDGYIWFLGRSDDVINASGYRIGPTEVENALVEHPAVSESAVVSSPDKDRGEVVKAFIVLNPEF 521

  Fly   590 EVFDQ-KLISDLKKMVRERIGPFAMPDVIQNAPGLPKTRSGKIMRRVLR 637
            ...|| :||.:|::.|:....|:..|..::....||||.:|||.|:.||
  Rat   522 LSHDQEQLIKELQEHVKSVTAPYKYPRKVEFVSELPKTITGKIKRKELR 570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AcCoAS	NP_001014599.2	PRK00174	7..665	CDD:234677	175/634 (28%)
		ACS	30..654	CDD:213313	175/634 (28%)
Acsm1	NP_001101972.2	AFD_class_I	46..573	CDD:302604	165/595 (28%)
		Acs	46..570	CDD:223442	163/593 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0365
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900