Protein Alignment AcCoAS and Acsm4

DIOPT Version :9

• Sequence 1: NP_001014599.2
• Gene: AcCoAS / 40348
• FlyBaseID: FBgn0012034
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_859046.1
• Gene: Acsm4 / 353317
• RGDID: 727928
• Length: 580
• Species: Rattus norvegicus
• Alignment Length: 656
• Identity: 190/656 - (28%)
• Similarity: 269/656 - (41%)
• Gaps: 149/656 - (22%)

  Fly    34 LDNPAEFWSRVAKQFH-----WETPADQDKF---------LKYNFNISKGPI---SIKWMEG--- 78
            |..||      .:.||     | .|...|.|         |..|||.:...:   |:|...|
  Rat    15 LAKPA------GRHFHRDPQLW-APLTLDDFEAINRCEKPLPKNFNFAADVLDQWSLKEKSGERP 72

  Fly    79 ASTNLCYNLLDRNVRNGLGDQIAYYWEGNHPDDYSRGLTYRKLLEEVCRFANVL-KDHGIRKGDR 142
            |:..|.:       .||.||::.  |........||            :.|||| |..|:::|||
  Rat    73 ANPALWW-------VNGKGDEVK--WSFQELGSLSR------------KAANVLTKPCGLQRGDR 116

  Fly   143 VSIYMPMILELPIAMLACARIGAVHSIVFAGFSPDSLAERMFDCKAKLLITADGAWRGEKPLYLK 207
            |::.:|.|.|..:..:||.|.|.|       |.|.::.          |...|..:|      |:
  Rat   117 VAVILPRIPEWWLINVACMRTGLV-------FMPGTIQ----------LTRKDILYR------LQ 158

  Fly   208 ALCDTALEKVEEMGHSVEKCIVVSHLKRVTPCQPDHVEEEIP------------WTDDRDYW--W 258
            |              |..||||.|  :.|.|. .|.:..|.|            |    |.|  :
  Rat   159 A--------------SKAKCIVAS--EEVAPA-VDSIASECPNLKTKLLVSPHRW----DGWLSF 202

  Fly   259 HEEME--DKEPACYPEWMDAEDPLFMLYTSGSTGKPKGVLHTTAGYLLYAATTFKIVFDYKPGDI 321
            .|.::  .:|..|..  ..:::|:.:.:|||:||.||...|:.:...:..|...:...|....||
  Rat   203 QELLQSASEEHNCVQ--TGSQEPMAIYFTSGTTGSPKMAQHSQSSLGIGYALCGRYWLDLTSSDI 265

  Fly   322 YWCTGDVGWITGHTYVVYGPLANGATSVIFEGTPFFPGNDRYWSVIDKYKVTQFYTAPTAIRAL- 385
            .|...|.|||......|:.....||...:.....|  ..|.:...:..|.:|...:|||..|.|
  Rat   266 MWNMSDTGWIKAAIGSVFSTWLRGACVFVHRMAQF--NTDTFLDTLTSYPITTLCSAPTVYRMLV 328

  Fly   386 ---MKFGEGPVLKHNLSGLKVLGSVGEPINPEAWLWYYKYIGKEQCSIVDTFWQTETGGHVITPL 447
               :|..:...|:|.|:|       |||:|||....:....|.|   :.:.:.|||.|  :|...
  Rat   329 QQDLKRYQFKRLRHCLTG-------GEPLNPEVLEQWKAQTGLE---LYEGYGQTEVG--IICAN 381

  Fly   448 PGATPMKPGSASFPFFGVKP---TLLDECG--IEIKGEGEGYLVFSQPWPGMMRTLY-NNHERFE 506
            .....:||||..   .||.|   .::||.|  :....|||..|......|....:.| :|.|:.:
  Rat   382 RKGEEIKPGSMG---KGVVPYDVQIIDEHGNILPSGKEGEIALRLGSDRPFCFFSEYVDNPEKTD 443

  Fly   507 DTYFSKFPGYYCTGDGARRDADGYLWITGRVDDMLNVSGHLMSTAEVESVLTEHPRVAESAVVSR 571
            .|....|   |.|||....|.|||||..||.||::..||:.:...||||.|.|||.|.||||||.
  Rat   444 ATIRRNF---YITGDRGVMDDDGYLWFVGRADDVIISSGYRIGPFEVESALIEHPAVVESAVVSS 505

  Fly   572 PHPVKGECLYCFIT-----PNENEVFDQKLISDLKKMVRERIGPFAMPDVIQNAPGLPKTRSGKI 631
            |.|::||.:..||.     .:.|.   :||.::|:..|:....|:..|..::....||||.:|||
  Rat   506 PDPIRGEVVKAFIVLAAPFKSSNR---EKLTAELQDHVKNSTAPYKYPRKVEFVQELPKTITGKI 567

  Fly   632 MRRVLR 637
            .|.|||
  Rat   568 KRNVLR 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AcCoAS	NP_001014599.2	PRK00174	7..665	CDD:234677	190/656 (29%)
		ACS	30..654	CDD:213313	190/656 (29%)
Acsm4	NP_859046.1	MACS_euk	48..577	CDD:341251	181/616 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0365
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810