Protein Alignment AcCoAS and acs1

DIOPT Version :10

• Sequence 1: NP_730611.1
• Gene: AcCoAS / 40348
• FlyBaseID: FBgn0012034
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_588291.2
• Gene: acs1 / 2539546
• PomBaseID: SPCC191.02C
• Length: 662
• Species: Schizosaccharomyces pombe
• Alignment Length: 668
• Identity: 299/668 - (44%)
• Similarity: 414/668 - (61%)
• Gaps: 48/668 - (7%)

  Fly     4 EKSIYDPNPAISQNAYISSFEEYQKFYQESLDNPAEFWSRVA-------KQFHWETPADQDKFLK 61
            :.::..||        |:|.:||::.|:||:::|:.||..:|       |||........||
pombe    21 DPTVPKPN--------IASLDEYKRMYEESINDPSTFWGNMARDMMTWDKQFSTVVQGSIDK--- 74

  Fly    62 YNFNISKGPISIKWMEGASTNLCYNLLDRNVRNGLGDQIAYYWEGNHPDDYSRGLTYRKLLEEVC 126
                     ....|....:.:.||||:||:. ....|.:|..:|.:.|:. .|.:|||:||..|.
pombe    75 ---------ADSAWFADGAISPCYNLVDRHA-IARPDAVALIYEADEPNQ-GRYITYRELLASVS 128

  Fly   127 RFANVLKDHGIRKGDRVSIYMPMILELPIAMLACARIGAVHSIVFAGFSPDSLAERMFDCKAKLL 191
            :.|..|:..|:..||||:||||||.|..|||||..|:||:||::|||||.:|:|:|:.|.:.|::
pombe   129 QCAGALQSMGVGMGDRVAIYMPMIPETIIAMLAIVRLGAIHSVIFAGFSAESVADRVNDSECKVI 193

  Fly   192 ITADGAWRGEKPLYLKALCDTALEKVEEMGHSVEKCIVVSHLKRVTPCQPDHVEEEIPWTDDRDY 256
            ||||.:.||.|.:.||.:.:.||.:..    :::|.:|...          ..|......:.||.
pombe   194 ITADESHRGGKRIPLKGVVNKALTECP----TIKKVLVFQR----------SAEPTASMVEGRDV 244

  Fly   257 WWHEEMEDKEPACYPEWMDAEDPLFMLYTSGSTGKPKGVLHTTAGYLLYAATTFKIVFDYKPGDI 321
            |||:.:......|.|..::.|.|||:|||||||||||||:|.|.||||.||.|.|.|||..|.|.
pombe   245 WWHDIIPKFPRYCPPAVVNPEHPLFLLYTSGSTGKPKGVVHCTGGYLLGAAATCKYVFDLHPTDR 309

  Fly   322 YWCTGDVGWITGHTYVVYGPLANGATSVIFEGTPFFPGNDRYWSVIDKYKVTQFYTAPTAIRALM 386
            ..|.|||||||||||:|||||..||.:::||.||.:|...|||||::::::||:|.||||||.|.
pombe   310 MGCAGDVGWITGHTYIVYGPLMLGAATLVFESTPAYPDYSRYWSVVERHRLTQWYIAPTAIRLLQ 374

  Fly   387 KFGEGPVLKHNLSGLKVLGSVGEPINPEAWLWYYKYIGKEQCSIVDTFWQTETGGHVITPLPGAT 451
            :.| ...:||:.|.|:|||||||||.||:::|||:.:|:::|::.||:||||||.|::|.|...|
pombe   375 RAG-NEFVKHDRSSLRVLGSVGEPIAPESFMWYYEVVGEKRCAVADTYWQTETGSHIVTSLGPVT 438

  Fly   452 PMKPGSASFPFFGVKPTLLDE-CGIEIKG-EGEGYLVFSQPWPGMMRTLYNNHERFEDTYFSKFP 514
            |||||||:.||||:...::|. .|..|:| :.||.|....|||...||::..|:|:.|||...:|
pombe   439 PMKPGSATLPFFGIDAVIIDPLTGKIIEGNDVEGVLAIRSPWPSAARTVWRGHDRYIDTYLKPYP 503

  Fly   515 GYYCTGDGARRDADGYLWITGRVDDMLNVSGHLMSTAEVESVLTEHPRVAESAVVSRPHPVKGEC 579
            |:|.|||||.||.|||:||.|||||::|:|||.:||||:|:.|..|..|||||||.....:.|:.
pombe   504 GFYFTGDGATRDKDGYIWIRGRVDDVVNISGHRLSTAEIEAALLSHDAVAESAVVGVHDELTGQA 568

  Fly   580 LYCFITPNENEVFDQKLISDLKKMVRERIGPFAMPDVIQNAPGLPKTRSGKIMRRVLRKIAVND- 643
            :..||..........:|..:|...||..|||||.|..:..: .||||||||||||:||||...:
pombe   569 VNAFILLKPGYEATVELEKELIMAVRSTIGPFASPRKLIFS-DLPKTRSGKIMRRILRKILAGEV 632

  Fly   644 RNVGDTSTLADEQIVEQL 661
            ..:||.|||||.::||.:
pombe   633 DQIGDLSTLADPKVVEHI 650

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AcCoAS	NP_730611.1	ACS	24..654	CDD:341270	291/639 (46%)
acs1	NP_588291.2	Ac_CoA_lig_AcsA	29..653	CDD:274022	297/652 (46%)