Protein Alignment AcCoAS and Acsm2

DIOPT Version :9

• Sequence 1: NP_001014599.2
• Gene: AcCoAS / 40348
• FlyBaseID: FBgn0012034
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_653349.1
• Gene: Acsm2 / 246263
• RGDID: 708383
• Length: 572
• Species: Rattus norvegicus
• Alignment Length: 628
• Identity: 150/628 - (23%)
• Similarity: 236/628 - (37%)
• Gaps: 139/628 - (22%)

  Fly    49 HWETPADQDKFLKYNF---------------NISKGPISIKWMEGASTNLCYNLLDRNVRNGLGD 98
            |.|.||      |:||               ..|.|| ::.||.|:...|.:|
  Rat    37 HQEVPA------KFNFASDVIDHWASLEKAGKRSPGP-ALWWMNGSGEELKWN------------ 82

  Fly    99 QIAYYWEGNHPDDYSRGLTYRKLLEEVCRFANVLKDH-GIRKGDRVSIYMPMILELPIAMLACAR 162
                               :|:|.|...:.||||... |:::||||::.:|.:.|..:..|.|.|
  Rat    83 -------------------FRELSEISKQTANVLTGACGLQRGDRVAVVLPRVPEWWLVTLGCMR 128

  Fly   163 IGAVHSIVFAGFSPDSLAERMFDCKAKLLITADGAWRGEKPLYLKALCDTALEKVEEMGHSVEKC 227
            .|.|............:..|:...||:.::..|                   |.|:|:......|
  Rat   129 SGLVFMPGTTQMKSTDILYRLQSSKARAIVAGD-------------------EVVQEVDAVAPDC 174

  Fly   228 IVVSHLKRVTPCQPDHVEEEIPWTDDRDYWWHEE--MEDKEPACYPEWMDAEDPLFMLYTSGSTG 290
            ..:. :|.:       |.|:     :|:.|.:.:  ::|..|........:::...:.:|||::|
  Rat   175 SFLK-IKLL-------VSEK-----NREGWLNFKALLKDASPIHQCVETVSQESAAIYFTSGTSG 226

  Fly   291 KPKGVLHTTAGYLLYAATTFKIVFD-----YKPGDIYWCTGDVGWITGHTYVVYGPLANGATSVI 350
            .||...|:      :.:...|...|     ..|.|..|...|.|||.........|...|....:
  Rat   227 PPKMAEHS------HCSLGLKAKMDAGWTGLGPSDTMWTISDTGWILNILGSFLEPWVLGTCIFV 285

  Fly   351 FEGTPFFPGNDRYWSVIDKYKVTQFYTAPTAIRALM-------KFGEGPVLKHNLSGLKVLGSVG 408
            .....|.|  .....|:..|.:.....||...|.|:       ||   |.|....||       |
  Rat   286 HLLPKFDP--QTVLKVLSSYPINTLLGAPLIYRMLLQQDLSSYKF---PHLHSCFSG-------G 338

  Fly   409 EPINP---EAWLWYYKYIGKEQCSIVDTFWQTETGGHVITPLPGATPMKPGSASFPFFGVKPTLL 470
            |.:.|   |:|.      .|....|.:.:.|||||  :...:.....:|||............::
  Rat   339 ETLLPETLESWK------AKTGLEIREIYGQTETG--ITCRVSRTMKVKPGYLGTAIVPYDVQVI 395

  Fly   471 DECGIEIKGEGEGYLVFS----QPWPGMMRTLYNNHERFEDTYFSKFPGYYCTGDGARRDADGYL 531
            ||.|..:....||.:...    :| .||.....:|.::.:......|   :..||...:|.:||.
  Rat   396 DEQGNVLPPGKEGDMALRVKPIRP-IGMFSGYVDNPKKTQANIRGDF---WLLGDRGIKDTEGYF 456

  Fly   532 WITGRVDDMLNVSGHLMSTAEVESVLTEHPRVAESAVVSRPHPVKGECLYCFI--TPNENEVFDQ 594
            ...||.||::|.||:.:..:|||:.|.|||.|.|:||:|.|.|::.|.:..|:  .|........
  Rat   457 HFMGRTDDIINSSGYRIGPSEVENALMEHPAVVETAVISSPDPIRREVVKAFVVLAPEFLSHDQD 521

  Fly   595 KLISDLKKMVRERIGPFAMPDVIQNAPGLPKTRSGKIMRRVLR 637
            :|...|::.|:....|:..|..::....||||.:|||.|..||
  Rat   522 QLTKVLQEHVKSVTAPYKYPRKVEFVLDLPKTITGKIERAKLR 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AcCoAS	NP_001014599.2	PRK00174	7..665	CDD:234677	150/628 (24%)
		ACS	30..654	CDD:213313	150/628 (24%)
Acsm2	NP_653349.1	AFD_class_I	40..568	CDD:302604	148/625 (24%)
		Acs	40..565	CDD:223442	148/625 (24%)
		Coenzyme A binding. /evidence=ECO:0000250	469..471		1/1 (100%)
		Coenzyme A binding. /evidence=ECO:0000250	540..542		0/1 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0365
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810