Protein Alignment AcCoAS and Acsm4

DIOPT Version :10

• Sequence 1: NP_730611.1
• Gene: AcCoAS / 40348
• FlyBaseID: FBgn0012034
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_848501.1
• Gene: Acsm4 / 233801
• MGIID: 2681844
• Length: 580
• Species: Mus musculus
• Alignment Length: 651
• Identity: 190/651 - (29%)
• Similarity: 266/651 - (40%)
• Gaps: 139/651 - (21%)

  Fly    34 LDNPAEFWSRVAKQFH-----WETPADQDKF---------LKYNFNISKGPI---SIKWMEG--- 78
            |..||      .:.||     | .|...|.|         |..|||.:...:   |:|...|
Mouse    15 LAKPA------GRHFHRDSQLW-APLTLDDFEAINRCEKPLPKNFNFAADVLDQWSLKEKSGERP 72

  Fly    79 ASTNLCYNLLDRNVRNGLGDQIAYYWEGNHPDDYSRGLTYRKLLEEVCRFANVL-KDHGIRKGDR 142
            |:..|.:       .||.||::.  |........||            :.|||| |..|:::|||
Mouse    73 ANPALWW-------VNGKGDEVK--WSFQELGSLSR------------KAANVLTKPCGLQRGDR 116

  Fly   143 VSIYMPMILELPIAMLACARIGAVHSIVFAGFSPDSLAERMFDCKAKLLITADGAWRGEKPLYLK 207
            |::.:|.|.|..:..:||.|.|.|       |.|.::.....|...:|..:             |
Mouse   117 VAVILPRIPEWWLINVACMRTGLV-------FMPGTIQLTRKDILYRLQAS-------------K 161

  Fly   208 ALCDTALEKVEEMGHS-VEKCIVVSHLKRVTPCQPDHVEEEIPWTDDRDYWWH-EEM---EDKEP 267
            |.|..|.|:|.....| |.:|   ..||......|.|      |    |.|.: :|:   ..:|.
Mouse   162 AKCIVASEEVAPAVDSIVSEC---PSLKTKLLVSPHH------W----DGWLNFQELLQSASEEH 213

  Fly   268 ACYPEWMDAEDPLFMLYTSGSTGKPKGVLHTTA----GYLLYAATTFKIVFDYKPGDIYWCTGDV 328
            .|..  ..:::|:.:.:|||:||.||...|:..    ||.|..    :...|....||.|...|.
Mouse   214 NCVE--TGSQEPMAIYFTSGTTGSPKMAQHSQGSLGIGYTLCG----RYWLDLTSSDIMWNMSDT 272

  Fly   329 GWITGHTYVVYGPLANGATSVIFEGTPFFPGNDRYWSVIDKYKVTQFYTAPTAIRAL----MKFG 389
            |||......|:.....||...:.....|  ..|.:...:..|.:|...:|||..|.|    :|..
Mouse   273 GWIKAAIGSVFSTWLRGACVFVHRMAQF--DTDIFLDTLTTYPITTLCSAPTVYRMLVQKDLKRY 335

  Fly   390 EGPVLKHNLSGLKVLGSVGEPINPEAWLWYYKYIGKEQCSIVDTFWQTETGGHVITPLPGATPMK 454
            :...|:|.|:|       |||:|||....:....|.|   :.:.:.|||.|  :|........:|
Mouse   336 QFKRLRHCLTG-------GEPLNPEVLEQWKMQTGLE---LYEGYGQTEVG--IICANRKGEAIK 388

  Fly   455 PGSASFPFFGVKP---TLLDECG--IEIKGEGEGYLVFSQPWPGMMRTLY-NNHERFEDTYFSKF 513
            |||..   .||.|   .::||.|  :....|||..|......|....:.| :|.|:.:.|....|
Mouse   389 PGSMG---KGVVPYDVQIIDENGNILPSGKEGEIALRLKSDRPFCFFSEYVDNPEKTDATIRRNF 450

  Fly   514 PGYYCTGDGARRDADGYLWITGRVDDMLNVSGHLMSTAEVESVLTEHPRVAESAVVSRPHPVKGE 578
               |.|||....|.|||.|..||.||::..||:.:...||||.|.|||.|.||||||.|.|::||
Mouse   451 ---YVTGDRGVMDDDGYFWFVGRADDVIISSGYRIGPFEVESALIEHPAVVESAVVSSPDPIRGE 512

  Fly   579 CLYCFIT-------PNENEVFDQKLISDLKKMVRERIGPFAMPDVIQNAPGLPKTRSGKIMRRVL 636
            .:..||.       .|.     :||.::|:..|:....|:..|..::....||||.:|||.|.||
Mouse   513 VVKAFIVLAAPYKCSNR-----EKLTAELQDHVKNSTAPYKYPRKVEFVQELPKTITGKIKRNVL 572

  Fly   637 R 637
            |
Mouse   573 R 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AcCoAS	NP_730611.1	ACS	24..654	CDD:341270	190/651 (29%)
Acsm4	NP_848501.1	MACS_euk	48..577	CDD:341251	181/611 (30%)