Protein Alignment AcCoAS and Acsm2

DIOPT Version :9

• Sequence 1: NP_001014599.2
• Gene: AcCoAS / 40348
• FlyBaseID: FBgn0012034
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_001171448.1
• Gene: Acsm2 / 233799
• MGIID: 2385289
• Length: 600
• Species: Mus musculus
• Alignment Length: 638
• Identity: 161/638 - (25%)
• Similarity: 247/638 - (38%)
• Gaps: 158/638 - (24%)

  Fly    49 HWETPADQDKFLKYNF---------------NISKGPISIKWMEGASTNLCYNLLDRNVRNGLGD 98
            |.|.||      |:||               ..|.|| ::.||                 ||.|.
Mouse    62 HQEAPA------KFNFASDVIDHWASVEKAGKRSSGP-ALWWM-----------------NGSGK 102

  Fly    99 QIAYYWEGNHPDDYSRGLTYRKLLEEVCRFANVLKDH-GIRKGDRVSIYMPMILELPIAMLACAR 162
            :|.:              ::|:|.|...:.||||... |:.:||||::.:|.|.|..:.:|.|.|
Mouse   103 EIKW--------------SFRELSEASKQTANVLSGACGLHRGDRVAVVLPRIPEWWLMILGCMR 153

  Fly   163 IGAVHSIVFAGFSPDSLAERMFD-------CKAKLLITADGAWRGEKPLYLKALCDTALEKVEEM 220
            .|.|       |.|.::..|..|       .||:.::..|                   |..:|:
Mouse   154 TGLV-------FMPGTIQMRSSDILYRLQASKARAIVAGD-------------------EVAQEV 192

  Fly   221 GHSVEKC------IVVSHLKRVTPCQPDHVEEEIPWTDDRDYWWHEEMEDKEPACYPEWMDAE-- 277
            ......|      ::||.                   :.|:.|.:.:...||.:...:.::.|
Mouse   193 DAVAPDCSFLKIKLLVSE-------------------NSREGWLNFKALLKEASTIHQCVETESR 238

  Fly   278 DPLFMLYTSGSTGKPKGVLHTTAGYLLYAATTFKIVFDYKPGDIYWCTGDVGWITGHTYVVYGPL 342
            :...:.:|||::|.||...|:.....:.|.............||.|...|..||.........|.
Mouse   239 ESAAIYFTSGTSGPPKMAEHSHCSLGIKAKMDAASWTGLSTSDIIWTISDTAWIMNILGAFLEPW 303

  Fly   343 ANGATSVIFEGTPFFPGNDRYWSVIDKYKVTQFYTAPTAIRALM-------KFGEGPVLKHNLSG 400
            ..|| .:.....|.| .:.....|:..|.:.....||...|.|:       ||   |.|....||
Mouse   304 VLGA-CIFVHLLPKF-DSQTVLKVLSSYPINTLVGAPIIYRMLLQQDLSSYKF---PHLHSCFSG 363

  Fly   401 LKVLGSVGEPINPEAWLWYYKYIGKEQCSIVDTFWQTETGGHVITPLPGATPMKPGSASFPFFGV 465
                   ||.:.||. |..:|  .|....|.:.:.|||||  :|..:.....:|||.....|...
Mouse   364 -------GETLLPET-LENWK--AKTGLEIREIYGQTETG--LICRVSRTMKVKPGYLGTAFAHY 416

  Fly   466 KPTLLDECGIEIKGEGEGYLVFS-QP-WP-GMMRTLYNNHERFEDTYFSKFPGYYCTGDGARRDA 527
            ...::||.|..:....||.:... :| || ||.....:|.::.:|.....|   :..||...:|.
Mouse   417 DVQVIDEQGNVLPPGKEGDIAIRVKPIWPIGMFSGYVDNPKKTQDNIRGDF---WLMGDRGIKDP 478

  Fly   528 DGYLWITGRVDDMLNVSGHLMSTAEVESVLTEHPRVAESAVVSRPHPVKGECLYCFITPNENEVF 592
            :||....||.||::|.||:.:..:|||:.|.|||.|:|:||:|.|.|.:||.:..|:      |.
Mouse   479 EGYFHFIGRSDDIINSSGYRIGPSEVENALMEHPAVSETAVISSPDPSRGEVVKAFV------VL 537

  Fly   593 DQKLIS----DLKKMVRERI----GPFAMPDVIQNAPGLPKTRSGKIMRRVLR 637
            ..:.:|    .|.|:::|.:    .|:..|..::....||||.:|||.|..||
Mouse   538 APEFLSHDRDQLTKVLQEHVKSVTAPYKYPRKVEFVLDLPKTVTGKIERAKLR 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AcCoAS	NP_001014599.2	PRK00174	7..665	CDD:234677	161/638 (25%)
		ACS	30..654	CDD:213313	161/638 (25%)
Acsm2	NP_001171448.1	Acs	65..591	CDD:223442	159/635 (25%)
		AFD_class_I	66..594	CDD:302604	159/634 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0365
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810