Protein Alignment AcCoAS and acs-19

DIOPT Version :9

• Sequence 1: NP_001014599.2
• Gene: AcCoAS / 40348
• FlyBaseID: FBgn0012034
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_001021205.1
• Gene: acs-19 / 175500
• WormBaseID: WBGene00007969
• Length: 680
• Species: Caenorhabditis elegans
• Alignment Length: 668
• Identity: 352/668 - (52%)
• Similarity: 470/668 - (70%)
• Gaps: 7/668 - (1%)

  Fly     4 EKSIYDPNPAISQNAYISSFEEYQKFYQESLDNPAEFWSRVAKQFHWETPADQDKFLKYNFNISK 68
            ::.|:.|...:...|:.:..:.|...|:.|:::..|||..|:.:.|:|  ....|.|::||:...
 Worm    18 DEDIFLPPAPLLAGAHCAGLQSYHDLYRSSINDADEFWRTVSSELHFE--QGTSKGLEWNFDSKA 80

  Fly    69 GPISIKWMEGASTNLCYNLLDRNVRNGLGDQIAYYWEGNHPDDYSRGLTYRKLLEEVCRFANVLK 133
            |.:.:|:|:||.||:.||.|:||::.|.|::|||.:|||.|.|.|. .||.:|..:|.:|:.||:
 Worm    81 GNVFVKFMDGAKTNISYNCLERNIKRGYGNKIAYIFEGNEPTDTST-WTYNELHAQVVQFSAVLR 144

  Fly   134 DHGIRKGDRVSIYMPMILELPIAMLACARIGAVHSIVFAGFSPDSLAERMFDCKAKLLITADGAW 198
            .||:::||.|::|:|||.||.:||||||||||:||:||||||.:|||.|:.|.:.::|:||||.:
 Worm   145 SHGVKRGDVVALYLPMIPELAVAMLACARIGAMHSVVFAGFSAESLAARVVDARCRVLVTADGVF 209

  Fly   199 RGEKPLYLKALCDTALEKVEEMGHSVEKCIVVSHLKRVTPCQPDHVE-EEIPWTDDRDYWWHEEM 262
            ||.||:.||::.|.|.....:....||..|:|.||||||  :||.|| .::.:||....:..|.:
 Worm   210 RGAKPIGLKSIADAAAVLASQEDVKVEAIIMVEHLKRVT--KPDGVELPKVDYTDITVIYDSEML 272

  Fly   263 EDKEPACYPEWMDAEDPLFMLYTSGSTGKPKGVLHTTAGYLLYAATTFKIVFDYKPGDIYWCTGD 327
            :........||||:|||||:||||||||||||:.||||||:.||..|.|..||.:..|:||||.|
 Worm   273 KCAGVDSPVEWMDSEDPLFILYTSGSTGKPKGIQHTTAGYMTYAYATTKYTFDAQEDDVYWCTAD 337

  Fly   328 VGWITGHTYVVYGPLANGATSVIFEGTPFFPGNDRYWSVIDKYKVTQFYTAPTAIRALMKFGEGP 392
            .||||||:|::||||.||...:.:||.|.:|...|.|.|.|||.||:.||:|||.||||..|...
 Worm   338 CGWITGHSYLLYGPLMNGLKGIWYEGVPTYPTPSRMWDVTDKYGVTKLYTSPTAARALMALGNQW 402

  Fly   393 VLKHNLSGLKVLGSVGEPINPEAWLWYYKYIGKEQCSIVDTFWQTETGGHVITPLPGATPMKPGS 457
            :...:...|||:|:|||||||.||:|.||.:|....|||||:||||||||:||.||||||||||:
 Worm   403 LESSSRKTLKVIGTVGEPINPAAWMWLYKQVGLSNVSIVDTYWQTETGGHMITCLPGATPMKPGA 467

  Fly   458 ASFPFFGVKPTLLDECGIEIKGEGEGYLVFSQPWPGMMRTLYNNHERFEDTYFSKFPGYYCTGDG 522
            |:.||||..|.|||..|..|:|.|||.|.|.:.||||||.:|.:.:||..||.:.|.|||.||||
 Worm   468 AAMPFFGASPVLLDAEGRVIEGPGEGSLCFDRAWPGMMRGIYGDEQRFVKTYLAPFNGYYFTGDG 532

  Fly   523 ARRDADGYLWITGRVDDMLNVSGHLMSTAEVESVLTEHPRVAESAVVSRPHPVKGECLYCFITPN 587
            ||||.||||||||||||::||||||:||||:||.|..|.:|||:|||:.||.:||...|.|:|.|
 Worm   533 ARRDEDGYLWITGRVDDLMNVSGHLLSTAEIESALVAHEKVAEAAVVAAPHDIKGSFPYAFVTLN 597

  Fly   588 ENEVFDQKLISDLKKMVRERIGPFAMPDVIQNAPGLPKTRSGKIMRRVLRKIAV-NDRNVGDTST 651
            ..|..::||:::|||:|||:||..|:|||||.|||||||||||:.||:|||||. ::..:|||:|
 Worm   598 VGERINEKLVAELKKLVREKIGALAVPDVIQEAPGLPKTRSGKVTRRILRKIAEGSESGIGDTTT 662

  Fly   652 LADEQIVEQLFANRPVEA 669
            |.||.:::||.:.|...|
 Worm   663 LVDESVIKQLISGRSARA 680

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AcCoAS	NP_001014599.2	PRK00174	7..665	CDD:234677	350/659 (53%)
		ACS	30..654	CDD:213313	342/625 (55%)
acs-19	NP_001021205.1	PRK00174	21..680	CDD:234677	351/663 (53%)
		ACS	44..665	CDD:213313	342/625 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160164097
Domainoid	1	1.000	517	1.000	Domainoid score	I154
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6469
Inparanoid	1	1.050	725	1.000	Inparanoid score	I321
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG61013
OrthoDB	1	1.010	-	-		D148550at33208
OrthoFinder	1	1.000	-	-		FOG0001357
OrthoInspector	1	1.000	-	-		oto18041
orthoMCL	1	0.900	-	-		OOG6_100430
Panther	1	1.100	-	-	LDO	PTHR24095
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R19
SonicParanoid	1	1.000	-	-		X954
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.940