Protein Alignment AcCoAS and acss2

DIOPT Version :10

• Sequence 1: NP_730611.1
• Gene: AcCoAS / 40348
• FlyBaseID: FBgn0012034
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: XP_004918553.1
• Gene: acss2 / 100486264
• XenbaseID: XB-GENE-1010924
• Length: 692
• Species: Xenopus tropicalis
• Alignment Length: 684
• Identity: 425/684 - (62%)
• Similarity: 516/684 - (75%)
• Gaps: 27/684 - (3%)

  Fly     7 IYDPNPAISQNAYISSFEEYQKFYQESLDNPAEFWSRVAKQFHWETPADQDKFLKYNFNISKGPI 71
            ::.|.|.:|..|:|.|:..||:.|:.|:.:|.|||..:|.:|||..|..| .||:|||:::||.|
 Frog     6 VFPPAPEVSAAAHIPSYARYQELYERSIRHPDEFWGEIANEFHWRVPPAQ-PFLRYNFDVTKGKI 69

  Fly    72 SIKWMEGASTNLCYNLLDRNVRN-GLGDQIAYYWEGNHPDDYSRGLTYRKLLEEVCRFANVLKDH 135
            .|:||:|..||:|||:|||||:: .|||:||:|||||.|.| |..:||.:||.:||:|||||:..
 Frog    70 FIEWMKGGVTNICYNVLDRNVQDKKLGDKIAFYWEGNEPGD-SMSITYSELLRKVCQFANVLRGQ 133

  Fly   136 GIRKGDRVSIYMPMILELPIAMLACARIGAVHSIVFAGFSPDSLAERMFDCKAKLLITADGAWRG 200
            ||:|||||||||||::||.:||||||||||:|||||||||.:||.||:.|....|||||||.:||
 Frog   134 GIKKGDRVSIYMPMVIELVVAMLACARIGAIHSIVFAGFSSESLCERILDSNCTLLITADGFFRG 198

  Fly   201 EKPLYLKALCDTALEKVEEMGHSVEKCIVVSHLKR-----------VTPC-------------QP 241
            :|.:.||::.|.||:|..|..:.:.||||:.||.|           ..||             :|
 Frog   199 DKLINLKSIADEALKKCAEKNYPLSKCIVLKHLGRDEIVSDGPSKISPPCKRQCPDLQGKKQEKP 263

  Fly   242 DHVEEEIPWTDDRDYWWHEEMEDKEPACYPEWMDAEDPLFMLYTSGSTGKPKGVLHTTAGYLLYA 306
            .....:|.|....|.||||.::|....|.|||.|:||.||:|||||||||||||:||..||::|.
 Frog   264 KRSHPQINWKPSVDMWWHELIKDASVECEPEWCDSEDELFILYTSGSTGKPKGVVHTVGGYMIYT 328

  Fly   307 ATTFKIVFDYKPGDIYWCTGDVGWITGHTYVVYGPLANGATSVIFEGTPFFPGNDRYWSVIDKYK 371
            |||||.||||.|.|:||||.|:||||||:|:.|||||||||||:|||.|.:|...|.|.:||||.
 Frog   329 ATTFKYVFDYHPDDVYWCTADIGWITGHSYLTYGPLANGATSVLFEGLPIYPDISRMWQIIDKYN 393

  Fly   372 VTQFYTAPTAIRALMKFGEGPVLKHNLSGLKVLGSVGEPINPEAWLWYYKYIGKEQCSIVDTFWQ 436
            |::|||||||||.|||:||.||.:::...|||||:||||||||||||||..:|.::|.|||||||
 Frog   394 VSKFYTAPTAIRLLMKYGEEPVKRYSRKSLKVLGTVGEPINPEAWLWYYNVVGDKRCPIVDTFWQ 458

  Fly   437 TETGGHVITPLPGATPMKPGSASFPFFGVKPTLLDECGIEIKGEGEGYLVFSQPWPGMMRTLYNN 501
            |||||||:|||||||..|||||:||||||.|.:|||.|.|::||.||||||.||||.:|||:|.|
 Frog   459 TETGGHVLTPLPGATTAKPGSATFPFFGVVPAILDESGEELEGEAEGYLVFKQPWPALMRTVYGN 523

  Fly   502 HERFEDTYFSKFPGYYCTGDGARRDADGYLWITGRVDDMLNVSGHLMSTAEVESVLTEHPRVAES 566
            .||||.|||.||||||.||||.|||.|||.|||||:||||||||||:|||||||.|.||..:||:
 Frog   524 QERFETTYFKKFPGYYVTGDGCRRDKDGYYWITGRIDDMLNVSGHLLSTAEVESALVEHSSIAEA 588

  Fly   567 AVVSRPHPVKGECLYCFITPNENEVFDQKLISDLKKMVRERIGPFAMPDVIQNAPGLPKTRSGKI 631
            ||||.||||||||||||:|..:...|...|:..|||:|||:|||.|.||.|||||||||||||||
 Frog   589 AVVSHPHPVKGECLYCFVTLRDGHEFTSTLVDQLKKLVREKIGPIATPDYIQNAPGLPKTRSGKI 653

  Fly   632 MRRVLRKIAVNDRNVGDTSTLADEQIVEQLFANR 665
            |||||||||.|||::||.|||||..:::|||.||
 Frog   654 MRRVLRKIAKNDRDLGDISTLADSTVIQQLFENR 687

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AcCoAS	NP_730611.1	ACS	24..654	CDD:341270	412/654 (63%)
acss2	XP_004918553.1	ACS	24..676	CDD:341270	412/653 (63%)