DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9391 and INM1

DIOPT Version :9

Sequence 1:	NP_649294.1	Gene:	CG9391 / 40346	FlyBaseID:	FBgn0037063	Length:	278	Species:	Drosophila melanogaster
Sequence 2:	NP_011912.1	Gene:	INM1 / 856442	SGDID:	S000001088	Length:	295	Species:	Saccharomyces cerevisiae

Alignment Length:	282	Identity:	102/282 - (36%)
Similarity:	161/282 - (57%)	Gaps:	22/282 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 VEKCL-EVASNLVSEAGRLIARNNEQRQDFVCK--SNDIDLVTQTDKDVEQLLMDGIRRHFPEHK 68
            :||.| |:|:..|   |.:|...:..::|:..|  |..:|:||..||.||:|:.:.::..:|..|
Yeast     8 IEKFLCELATEKV---GPIIKSKSGTQKDYDLKTGSRSVDIVTAIDKQVEKLIWESVKTQYPTFK 69

  Fly    69 FIGEEESSGAEGVKKLTDEPTWIIDPVDGTMNFVHAFPHSCISVGLKVNKVTELGLVYNPILEQR 133
            |||||  |..:|...:||:||:||||:|||.||||.||.||.|:||.|||...:|::|||.:...
Yeast    70 FIGEE--SYVKGETVITDDPTFIIDPIDGTTNFVHDFPFSCTSLGLTVNKEPVVGVIYNPHINLL 132

  Fly   134 FTARRGHGAFYNGR------RIHVSGQKELGKALVTSEFGTTRDEAKMKVVHENFEKMAK----K 188
            .:|.:|:|...|.:      ::...|...|.|::|..:.|:.|:....:.....:||:..    .
Yeast   133 VSASKGNGMRVNNKDYDYKSKLESMGSLILNKSVVALQPGSAREGKNFQTKMATYEKLLSCDYGF 197

  Fly   189 AHGLRVLGSAALNMSMVALGAADANYEFGIHAWDVCAGDLIVREAGGVVIDPAGGEF--DIMSRR 251
            .||.|.|||:|:.|:.:|:|..|:.::.|.::||||||..|::|.||.|:....||:  |:.:|.
Yeast   198 VHGFRNLGSSAMTMAYIAMGYLDSYWDGGCYSWDVCAGWCILKEVGGRVVGANPGEWSIDVDNRT 262

  Fly   252 VLA--AATPELAQEISKVLTQF 271
            .||  ......:.|.:|.:|.|
Yeast   263 YLAVRGTINNESDEQTKYITDF 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9391	NP_649294.1	IMPase	10..255	CDD:238817	96/261 (37%)
INM1	NP_011912.1	IMPase	10..267	CDD:238817	97/261 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345823
Domainoid	1	1.000	169	1.000	Domainoid score	I783
eggNOG	1	0.900	-	-		E1_COG0483
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4043
Inparanoid	1	1.050	169	1.000	Inparanoid score	I1019
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54074
OrthoFinder	1	1.000	-	-		FOG0000745
OrthoInspector	1	1.000	-	-		mtm9175
orthoMCL	1	0.900	-	-		OOG6_100401
Panther	1	1.100	-	-	O	PTHR20854
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2586
SonicParanoid	1	1.000	-	-		X706
TreeFam	1	0.960	-	-
	15	14.790