DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9391 and impa2

DIOPT Version :9

Sequence 1:	NP_649294.1	Gene:	CG9391 / 40346	FlyBaseID:	FBgn0037063	Length:	278	Species:	Drosophila melanogaster
Sequence 2:	NP_001018408.1	Gene:	impa2 / 553595	ZFINID:	ZDB-GENE-050522-349	Length:	275	Species:	Danio rerio

Alignment Length:	275	Identity:	125/275 - (45%)
Similarity:	182/275 - (66%)	Gaps:	5/275 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 DVEKCLEVASNLVSEAGRLIARNNEQRQDFVCKSNDIDLVTQTDKDVEQLLMDGIRRHFPEHKFI 70
            |..:||:||.::...||::::...:..:....||...||||:.|..||:|::..:|..:|.|:||
Zfish     3 DWSECLDVAVDIARRAGQMVSCAVQLEKRVSSKSTPTDLVTEADHQVEELIISTLREKYPTHRFI 67

  Fly    71 GEEESSGAEGVK-KLTDEPTWIIDPVDGTMNFVHAFPHSCISVGLKVNKVTELGLVYNPILEQRF 134
            |||  |.|.||| :|||.|||||||:|||.||||:||...:|:|..|.|..|.|::|:......:
Zfish    68 GEE--SSAAGVKCELTDSPTWIIDPIDGTCNFVHSFPMVAVSIGFAVRKELEFGVIYHCFDGTLY 130

  Fly   135 TARRGHGAFYNGRRIHVSGQKELGKALVTSEFGTTRDEAKMKVVHENFEK-MAKKAHGLRVLGSA 198
            |||:|||||.||.|:.||.:|::.|||:.:|.|..||.|.:.:...|.:| ::...||:|::||:
Zfish   131 TARKGHGAFCNGVRLQVSKEKDVSKALILTEIGAKRDSATLDIFLGNMKKILSAPTHGVRIIGSS 195

  Fly   199 ALNMSMVALGAADANYEFGIHAWDVCAGDLIVREAGGVVIDPAGGEFDIMSRRVLAAATPELAQE 263
            .|::..||.|||:|.|::|:|.||:.|..:|:|||||.|:|..||..|:|||||:||.|.|:|:.
Zfish   196 TLSLCQVASGAAEAYYQYGLHCWDIAAAAVIIREAGGCVMDTTGGPLDLMSRRVVAAGTREIAEY 260

  Fly   264 ISKVLTQFNPLPRDD 278
            :.|.|...| ..|||
Zfish   261 VVKQLQPIN-YGRDD 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9391	NP_649294.1	IMPase	10..255	CDD:238817	113/246 (46%)
impa2	NP_001018408.1	IMPase	7..252	CDD:238817	113/246 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	243	1.000	Domainoid score	I2166
eggNOG	1	0.900	-	-		E1_COG0483
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	248	1.000	Inparanoid score	I3236
OMA	1	1.010	-	-		QHG54074
OrthoDB	1	1.010	-	-		D406919at33208
OrthoFinder	1	1.000	-	-		FOG0000745
OrthoInspector	1	1.000	-	-		mtm6554
orthoMCL	1	0.900	-	-		OOG6_100401
Panther	1	1.100	-	-	O	PTHR20854
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2586
SonicParanoid	1	1.000	-	-		X706
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.870