DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9391 and impa1

DIOPT Version :9

Sequence 1:	NP_649294.1	Gene:	CG9391 / 40346	FlyBaseID:	FBgn0037063	Length:	278	Species:	Drosophila melanogaster
Sequence 2:	NP_001002745.1	Gene:	impa1 / 437018	ZFINID:	ZDB-GENE-040718-245	Length:	282	Species:	Danio rerio

Alignment Length:	272	Identity:	122/272 - (44%)
Similarity:	178/272 - (65%)	Gaps:	3/272 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 EKCLEVASNLVSEAGRLIARNNEQRQDFVCKSNDIDLVTQTDKDVEQLLMDGIRRHFPEHKFIGE 72
            :..::.|..|..:||.::....:.....:|||:.:||||:||::||||::..::..||||.||||
Zfish     6 QDAMDHAVTLARKAGEIVREALQNDLKIMCKSSSVDLVTKTDQNVEQLIITSVKEKFPEHSFIGE 70

  Fly    73 EESSGAEGVKKLTDEPTWIIDPVDGTMNFVHAFPHSCISVGLKVNKVTELGLVYNPILEQRFTAR 137
            |..:..|.. .||:.||||:||||||.||||.:|...:|:|..|||..|.|:||:.|.::.:|||
Zfish    71 ESVAAGEPC-VLTENPTWIVDPVDGTTNFVHGYPFVAVSIGFAVNKTLEFGVVYSCIEDKMYTAR 134

  Fly   138 RGHGAFYNGRRIHVSGQKELGKALVTSEFGTTRDEAKMKVVHENFEK-MAKKAHGLRVLGSAALN 201
            :|.|||.||:.:.||.|||:.::::.:|||:.||...::.:..:..| :....||:|..||||:|
Zfish   135 KGKGAFCNGQPLQVSDQKEINQSIIATEFGSNRDPENVEKIFSSMRKILCLPVHGIRGAGSAAIN 199

  Fly   202 MSMVALGAADANYEFGIHAWDVCAGDLIVREAGGVVIDPAGGEFDIMSRRVLAAATPELAQEISK 266
            |.:||.|..:|.||.|||.||:.||.:||.|||||::|..||.||:||||||||....:.:.|.:
Zfish   200 MCLVAAGCVEAYYEIGIHCWDMAAGAVIVSEAGGVLLDVEGGPFDLMSRRVLAANNKTIGERIVQ 264

  Fly   267 VLTQFNPLPRDD 278
            .:..| |..|||
Zfish   265 EVEAF-PAVRDD 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9391	NP_649294.1	IMPase	10..255	CDD:238817	114/245 (47%)
impa1	NP_001002745.1	IMPase	9..254	CDD:238817	115/245 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	243	1.000	Domainoid score	I2166
eggNOG	1	0.900	-	-		E1_COG0483
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4043
Inparanoid	1	1.050	248	1.000	Inparanoid score	I3236
OMA	1	1.010	-	-		QHG54074
OrthoDB	1	1.010	-	-		D406919at33208
OrthoFinder	1	1.000	-	-		FOG0000745
OrthoInspector	1	1.000	-	-		mtm6554
orthoMCL	1	0.900	-	-		OOG6_100401
Panther	1	1.100	-	-	LDO	PTHR20854
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2586
SonicParanoid	1	1.000	-	-		X706
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.870