Protein Alignment CG9391 and IMPA2

DIOPT Version :9

• Sequence 1: NP_649294.1
• Gene: CG9391 / 40346
• FlyBaseID: FBgn0037063
• Length: 278
• Species: Drosophila melanogaster
• Sequence 2: NP_055029.1
• Gene: IMPA2 / 3613
• HGNCID: 6051
• Length: 288
• Species: Homo sapiens
• Alignment Length: 273
• Identity: 128/273 - (46%)
• Similarity: 181/273 - (66%)
• Gaps: 5/273 - (1%)

  Fly     8 EKCLEVASNLVSEAGRLIARNNEQRQDFVCKSNDIDLVTQTDKDVEQLLMDGIRRHFPEHKFIGE 72
            |:|.:.|..|...||::|.:...:.:....|::..||||:||..||.|::..:|..||.|:||.|
Human    17 EECFQAAVQLALRAGQIIRKALTEEKRVSTKTSAADLVTETDHLVEDLIISELRERFPSHRFIAE 81

  Fly    73 E-ESSGAEGVKKLTDEPTWIIDPVDGTMNFVHAFPHSCISVGLKVNKVTELGLVYNPILEQRFTA 136
            | .:|||:.|  ||..|||||||:|||.||||.||...:|:|..|.:..|.|::|:...|:.:|.
Human    82 EAAASGAKCV--LTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGVIYHCTEERLYTG 144

  Fly   137 RRGHGAFYNGRRIHVSGQKELGKALVTSEFGTTRDEAKMKVVHENFEKMA-KKAHGLRVLGSAAL 200
            |||.|||.||:|:.|||:.:|.||||.:|.|..||.|.:|:...|.|::. .||||:||:||:.|
Human   145 RRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMERLLHAKAHGVRVIGSSTL 209

  Fly   201 NMSMVALGAADANYEFGIHAWDVCAGDLIVREAGGVVIDPAGGEFDIMSRRVLAAATPELAQEIS 265
            .:..:|.|||||.|:||:|.||:.|..:|:|||||:|||.:||..|:|:.||:||:|.|:|..|:
Human   210 ALCHLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGGPLDLMACRVVAASTREMAMLIA 274

  Fly   266 KVLTQFNPLPRDD 278
            :.|...| ..|||
Human   275 QALQTIN-YGRDD 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9391	NP_649294.1	IMPase	10..255	CDD:238817	116/246 (47%)
IMPA2	NP_055029.1	IMPase	19..265	CDD:238817	117/247 (47%)
		Substrate binding	103..106		1/2 (50%)
		Substrate binding	205..207		1/1 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	243	1.000	Domainoid score	I2217
eggNOG	1	0.900	-	-		E1_COG0483
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	250	1.000	Inparanoid score	I3238
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54074
OrthoDB	1	1.010	-	-		D406919at33208
OrthoFinder	1	1.000	-	-		FOG0000745
OrthoInspector	1	1.000	-	-		mtm8602
orthoMCL	1	0.900	-	-		OOG6_100401
Panther	1	1.100	-	-	O	PTHR20854
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2586
SonicParanoid	1	1.000	-	-		X706
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.870