DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9391 and Impa2

DIOPT Version :9

Sequence 1:	NP_649294.1	Gene:	CG9391 / 40346	FlyBaseID:	FBgn0037063	Length:	278	Species:	Drosophila melanogaster
Sequence 2:	NP_757378.1	Gene:	Impa2 / 282636	RGDID:	628692	Length:	290	Species:	Rattus norvegicus

Alignment Length:	273	Identity:	128/273 - (46%)
Similarity:	181/273 - (66%)	Gaps:	5/273 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 EKCLEVASNLVSEAGRLIARNNEQRQDFVCKSNDIDLVTQTDKDVEQLLMDGIRRHFPEHKFIGE 72
            ::|.|||..|...||::|.:...:.:....|::..||||:||..||.|::..:|:.||.|:||.|
  Rat    19 DECFEVAVQLALRAGQIIRKALTEEKHVSTKTSAADLVTETDHRVEDLIVSELRKRFPSHRFIAE 83

  Fly    73 E-ESSGAEGVKKLTDEPTWIIDPVDGTMNFVHAFPHSCISVGLKVNKVTELGLVYNPILEQRFTA 136
            | .:|||:.|  ||..|||||||:|||.||||.||...:|:|..|::..|.|::::...|:.:|.
  Rat    84 EATASGAKCV--LTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVHQELEFGVIHHCTEERLYTG 146

  Fly   137 RRGHGAFYNGRRIHVSGQKELGKALVTSEFGTTRDEAKMKVVHENFEKMA-KKAHGLRVLGSAAL 200
            |||.|||.||:|:.||.:.:|.||||.:|.|..||...:||...|.|::. .||||:||:||:.|
  Rat   147 RRGQGAFCNGQRLQVSRETDLAKALVLTEIGPKRDPDTLKVFLSNMERLLHAKAHGVRVIGSSTL 211

  Fly   201 NMSMVALGAADANYEFGIHAWDVCAGDLIVREAGGVVIDPAGGEFDIMSRRVLAAATPELAQEIS 265
            .:..:|.|||||.|:||:|.||:.|..:|:|||||:|||.:||..|:||.||:||.|.|:|..|:
  Rat   212 ALCYLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGGPLDLMSCRVVAAGTREMAVLIA 276

  Fly   266 KVLTQFNPLPRDD 278
            :.|...| ..|||
  Rat   277 QALQTIN-YGRDD 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9391	NP_649294.1	IMPase	10..255	CDD:238817	117/246 (48%)
Impa2	NP_757378.1	IMPase	21..266	CDD:238817	117/246 (48%)
		Substrate binding. /evidence=ECO:0000250	105..108		1/2 (50%)
		Substrate binding. /evidence=ECO:0000250	207..209		1/1 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	242	1.000	Domainoid score	I2160
eggNOG	1	0.900	-	-		E1_COG0483
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	248	1.000	Inparanoid score	I3170
OMA	1	1.010	-	-		QHG54074
OrthoDB	1	1.010	-	-		D406919at33208
OrthoFinder	1	1.000	-	-		FOG0000745
OrthoInspector	1	1.000	-	-		mtm9083
orthoMCL	1	0.900	-	-		OOG6_100401
Panther	1	1.100	-	-	O	PTHR20854
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X706
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.840