Protein Alignment Eip78C and nr1i2

DIOPT Version :10

• Sequence 1: NP_524195.2
• Gene: Eip78C / 40345
• FlyBaseID: FBgn0004865
• Length: 862
• Species: Drosophila melanogaster
• Sequence 2: NP_001092087.2
• Gene: nr1i2 / 565875
• ZFINID: ZDB-GENE-030903-3
• Length: 430
• Species: Danio rerio
• Alignment Length: 538
• Identity: 118/538 - (21%)
• Similarity: 198/538 - (36%)
• Gaps: 135/538 - (25%)

  Fly   327 QLQHPQQQQSFG-LADSSSSNGSSNNNNGVSSKSFVPCKVCGDKASGYHYGVTSCEGCKGFFRRS 390
            ||:..::.:... |.||...:||............  |:|||||::|||:...:||||||||||:
Zfish    11 QLRMSKEMEELSPLDDSGHGDGSEEETEEDDEPKI--CQVCGDKSTGYHFNAMTCEGCKGFFRRA 73

  Fly   391 IQKQIEYRCLRDGKCLVIRLNRNRCQYCRFKKCLSAGMSRDSVRYGRVPKRSRELNGAAASSAAA 455
            :::..:..|.....|::.:.||.:||.||.:||||.||.|:.:......::.|
Zfish    74 MKRPAQLCCPFQSACVITKSNRRQCQSCRLQKCLSIGMKRELIMSDEAVEKRR------------ 126

  Fly   456 GAPASLNVDDSTSSTLHPSHLQQQQQQHLLQQQQQQQHQPQLQQH---------HQLQQQPHVSG 511
                           |.....:.|::...|..||:...|..|..|         |..|.:|...|
Zfish   127 ---------------LQIRRKRMQEEPVTLTPQQEAVIQELLNAHKKTFDMTCAHFSQFRPLDRG 176

  Fly   512 VRVKTPSTPQTPQMCSIASSPSELGGCNSANNNNNNNNNSSSGNASGGSGVSVGVVVVGGHQQLV 576
            .:..:.|.|.|
Zfish   177 QKSVSESIPVT------------------------------------------------------ 187

  Fly   577 GGSMVGMAGMGTDAHQVGMCHDGLAGTANELTVYDVIMCVSQAHRLNCSYTEELTRELMRRPVTV 641
            .||.:....:..|..|.......|:.:::.....|    ..:.|..:.|:|            ::
Zfish   188 NGSWIDHRPIAEDPVQWVFNSTSLSSSSSSCQSLD----KEKKHFKSGSFT------------SL 236

  Fly   642 PQNGIASTVAESLEFQKIWLWQQFSARVTPGVQRIVEFAKRVPGFCDFTQDDQLILIKLGFFEVW 706
            |                     .|:...|..::.::.|.|.:..|.....:||:.|:|...||:.
Zfish   237 P---------------------HFTDLTTYMIKNVINFGKTLTMFRALVMEDQISLLKGATFEII 280

  Fly   707 LTHVARLINEATLTLDDG--AYLTRQQLEILYDSDFVNALLNFANTLNAYGLSDTEIGLFSAMVL 769
            |.|.....||.|...:.|  .|.........:....::.::||..||....|.:.|..|..|:.|
Zfish   281 LIHFNMFFNEVTGIWECGPLQYCMDDAFRAGFQHHLLDPMMNFHYTLRKLRLHEEEYVLMQALSL 345

  Fly   770 LASDRAGLSEPKVIGRARELVAEALRVQILRSRAGSPQALQLMPALEAKIPELRSLGAKHFSHLD 834
            .:.||.|:::.|||.|.:|.:|..|:..|...|.| |:...|.|.:...:.|:||:..::...:
Zfish   346 FSPDRPGVTDHKVIDRNQETLALTLKTYIEAKRNG-PEKNLLFPKIMGCLTEMRSMNEEYTKQV- 408

  Fly   835 WLRMNWTKLRLPPLFAEI 852
             |::...:..:.||:.||
Zfish   409 -LKIQDMQPEVSPLWLEI 425

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eip78C	NP_524195.2	NR_DBD_DmE78_like	363..443	CDD:143539	34/79 (43%)
		NR_LBD_DmE78_like	659..854	CDD:132739	51/196 (26%)
nr1i2	NP_001092087.2	NR_DBD_PXR	45..131	CDD:143536	36/114 (32%)
		NR_LBD_PXR_like	141..425	CDD:132732	72/377 (19%)