Protein Alignment Eip78C and nr1d2b

DIOPT Version :9

• Sequence 1: NP_001246862.1
• Gene: Eip78C / 40345
• FlyBaseID: FBgn0004865
• Length: 862
• Species: Drosophila melanogaster
• Sequence 2: NP_571140.1
• Gene: nr1d2b / 30271
• ZFINID: ZDB-GENE-990415-244
• Length: 578
• Species: Danio rerio
• Alignment Length: 678
• Identity: 191/678 - (28%)
• Similarity: 275/678 - (40%)
• Gaps: 205/678 - (30%)

  Fly   241 SSSAAHSSPDSGCSSASSSGSSRSCGSSSASSSSSAVSSTISSGRSSNNSVVNPAATSSSVAHLN 305
            |||::.|||:| |.|.||:.|.:||
Zfish    14 SSSSSASSPES-CHSDSSNSSFQSC---------------------------------------- 37

  Fly   306 KEQQQQPLPTTQLQQQQQHQQQLQHPQQQQSFGLADSSSSNGSSNNNNGVSSKSFVPCKVCGDKA 370
                 .|..|.|.|.:..|......|.:.........||:.......||:    .:.||||||.|
Zfish    38 -----SPPHTGQGQGETLHVASHSRPPRHGGGKARSLSSTKSGITKINGL----VLLCKVCGDVA 93

  Fly   371 SGYHYGVTSCEGCKGFFRRSIQKQIEY-RCLRDGKCLVIRLNRNRCQYCRFKKCLSAGMSRDSVR 434
            ||:||||.:|||||||||||||:.|:| :||::..|.::|:||||||.|||||||..|||||:||
Zfish    94 SGFHYGVHACEGCKGFFRRSIQQNIQYKKCLKNESCPIMRINRNRCQQCRFKKCLLVGMSRDAVR 158

  Fly   435 YGRVPKRSRE----------------------LNGAAASSAAAGAPASLNVDDSTS--STLHPS- 474
            :||:|||.::                      ||.  .:|||.|.......:||||  |:..||
Zfish   159 FGRIPKREKQRMLLEMQNAMNNMMNNSHGNQSLNN--QTSAADGTSEDGTSEDSTSGPSSRSPSS 221

  Fly   475 -------------HLQ----------------------------QQQQQHLLQQQQQQQHQPQLQ 498
                         .||                            ..|:..:..|:|.......|.
Zfish   222 SPRSNRSESSPDPELQIAMDTSSSSDSSSATDSGEEEVIGTVTRAHQETFMYNQEQGSMASEALN 286

  Fly   499 QHHQ--------LQQQPHVSGVRVKTPST---PQTPQ-----MCSIASSPSELGGCNSANNNNNN 547
            .:..        |..|.:||.|..:.|.:   ||.|:     ..:::|.|..|
Zfish   287 NYSHCTEKTQEVLNHQNNVSSVSEQNPQSSCGPQGPEDSGQDYSTLSSCPVRL------------ 339

  Fly   548 NNNSSSGNASGGSGVSVGVVVVGGHQQLVGGSMVGMAGMGTDAHQVGMCHDGLAGTANELTVYDV 612
            :||||       .|.|:..:....|..             .:.|..|..               :
Zfish   340 SNNSS-------RGPSLQTLTFRAHND-------------HETHANGSY---------------I 369

  Fly   613 IMCVSQAHRLNCSYTEELTRELMRRPVTVPQNGIASTVAESLEFQKIWLWQQFSARVTPGVQRIV 677
            :....:|:|::      |...:...|...||....|            :|::||...||.|:.:|
Zfish   370 VPTFPRANRMH------LVCPMNTSPYVDPQKSGHS------------IWEEFSMSFTPAVREVV 416

  Fly   678 EFAKRVPGFCDFTQDDQLILIKLGFFEVWLTHVARL--INEATLTLDDGAYLTRQQLEILYDSDF 740
            |||||:|||.|.:|.||:.|:|.|.|||.:.....|  :.|..:|...|...:...|..|...|.
Zfish   417 EFAKRIPGFKDLSQHDQVSLLKAGTFEVLVVRFTSLFDVKERKVTFLSGRKYSVDALRSLGAGDL 481

  Fly   741 VNALLNFANTLNAYGLSDTEIGLFSAMVLLASDRAGLSEPKVIGRARELVAEALRVQILRSRAGS 805
            :|::.:|...|.|..||:.|:.||:|:||:::||:||.....:...:|.:..|||..|.::.
Zfish   482 LNSMFDFTEKLQALNLSEEEMSLFTAVVLVSADRSGLENVNSVEALQETLIRALRSLITKNH--- 543

  Fly   806 PQALQLMPALEAKIPELRSLGAKHFSHL 833
            |..:.:...|..|:|:||||...|...|
Zfish   544 PNEIAIFTKLLLKLPDLRSLNNMHSEQL 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eip78C	NP_001246862.1	NR_DBD_DmE78_like	363..443	CDD:143539	57/80 (71%)
		NR_LBD_DmE78_like	659..854	CDD:132739	63/177 (36%)
nr1d2b	NP_571140.1	NR_DBD_REV_ERB	81..169	CDD:143540	58/91 (64%)
		NR_LBD_REV_ERB	388..576	CDD:132738	67/199 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4846
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	232	1.000	Inparanoid score	I3402
OMA	1	1.010	-	-		QHG47784
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.870