Protein Alignment Eip78C and nhr-188

DIOPT Version :10

• Sequence 1: NP_524195.2
• Gene: Eip78C / 40345
• FlyBaseID: FBgn0004865
• Length: 862
• Species: Drosophila melanogaster
• Sequence 2: NP_504064.1
• Gene: nhr-188 / 185912
• WormBaseID: WBGene00018544
• Length: 353
• Species: Caenorhabditis elegans
• Alignment Length: 342
• Identity: 76/342 - (22%)
• Similarity: 122/342 - (35%)
• Gaps: 91/342 - (26%)

  Fly   358 KSFVPCKVCGDKASGYHYGVTSCEGCKGFFRRSIQKQIEYRCLRDGKCLVIRLN----RNRCQYC 418
            :|.:.|.:||..||.::|||.:|..||.||||.:.:||.|:|....|||.   |    :.||:.|
 Worm    12 RSTLKCLICGRNASCHNYGVLTCNACKMFFRRVVIEQITYQCRNWKKCLE---NADQFKPRCKAC 73

  Fly   419 RFKKCLSAGMSRDSVRYGRVPKRSRELNGAAASSAAAGAPASLNVDDSTSSTLHPSHLQQQQQQH 483
            ||:||:..||....:...::.|                          |....||........|.
 Worm    74 RFEKCVRLGMKLGPIAMEKLYK--------------------------TKPMSHPDFATNALIQE 112

  Fly   484 LLQQQQQQQHQ---------PQLQQHHQLQQQPHVSGVRVKTPSTPQTPQMCSIASSPSE----- 534
            :|.....::::         |.|:   ::.|....||::.||..     |..|:|....:
 Worm   113 VLYLNYTKRYKLCNFYTSENPTLE---EMVQTTFWSGMKRKTEK-----QEISVAEWSFQATYIA 169

  Fly   535 ------LGGCNSANNNNN----NNNNSSS---GNASGGSGVSVGVVVVGGHQQLVGGSMVGMAGM 586
                  |...|...|:..    .|.:|.|   .:|.......|..|.....:.:....::.|...
 Worm   170 VETFLSLEFMNLIENDEKVVLLRNFSSKSIVLDSAMRALNAKVDRVTTPDGEDIYSDIILSMFSA 234

  Fly   587 GTDAHQVGMCHDGLAGTANELTVYD--------VIMCVSQAHRLNCSYTEELTRELMRRPVTVPQ 643
            |.    :.....||.....||.|.:        ::.|....|.|:         |..||.:...|
 Worm   235 GF----LNSIQCGLVSRVAELKVTELEHAMLSVLLFCNPAIHPLS---------ERTRRLLATRQ 286

  Fly   644 NGIASTVAE--SLEFQK 658
            ...:||:.:  .|.:|:
 Worm   287 KSYSSTLLQYCLLSYQQ 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eip78C	NP_524195.2	NR_DBD_DmE78_like	363..443	CDD:143539	33/83 (40%)
		NR_LBD_DmE78_like	659..854	CDD:132739	76/342 (22%)
nhr-188	NP_504064.1	ZnF_C4	16..84	CDD:197701	31/70 (44%)
		HOLI	162..322	CDD:214658	27/155 (17%)