Protein Alignment CG10508 and wwc1

DIOPT Version :9

• Sequence 1: NP_001246859.1
• Gene: CG10508 / 40342
• FlyBaseID: FBgn0037060
• Length: 733
• Species: Drosophila melanogaster
• Sequence 2: XP_689275.5
• Gene: wwc1 / 560785
• ZFINID: ZDB-GENE-091118-8
• Length: 1112
• Species: Danio rerio
• Alignment Length: 862
• Identity: 160/862 - (18%)
• Similarity: 282/862 - (32%)
• Gaps: 290/862 - (33%)

  Fly     9 KMPPGWDCKYDQATGNCYYINYLTKAMQLEDPRGRSYRQLQNERCSTESIALQQL--VSQPQTSH 71
            ::|.||:..||...| .||:::.||:.||||||.:..|:        :.:.|...  |.|...|.
Zfish    54 ELPVGWEEAYDPHVG-AYYVDHNTKSTQLEDPRAQWQRE--------QELMLHDYLNVVQEALSA 109

  Fly    72 NSSPYHVHPSNNLTAIRAFQE---------RQQPTLHNISTS-----------PLLSASSRGHLE 116
            ....|.|.......|.:.:::         ..|.:|::.|:|           .:::|.||.: :
Zfish   110 QKEIYQVKEQRLRLAQQEYRQLNDAWRDKSSSQTSLNSRSSSSSKYDPEILKAEIVTAKSRVN-K 173

  Fly   117 MSSPLPFQRARVGPNLSRRSTIQETSFTTQAETDAVVTKIQNMFPTAGENHIRLLLKRYYNSEAV 181
            :...|.:.:..:        ..:|..|.|..|.|..|:...:.:             :.:.::|:
Zfish   174 LKRDLAYMKQEL--------HYKEQGFETLKEIDHKVSSASHGY-------------KLHEAQAI 217

  Fly   182 VVSALQVEKHPVTMPGPFVTPPSQRHLFHSGSAFYMTPPARRPDTVASRRTSRTASPLPGGRFGS 246
            :.....::                                   |.::|....:..      ....
Zfish   218 LKEVKSIK-----------------------------------DAISSGEKEKQE------LMRK 241

  Fly   247 LVSVQSGPGGPSGHQAVLPPSSAVPPALHGSPLWRSSPRPHSSPKMKLRYMKNIFPKADEELLLD 311
            |..::.|.....|.|:.|..|:   |:|..|.|  |.||.:|                |.|...|
Zfish   242 LAVLKDGFQLDYGSQSDLWASN---PSLANSNL--SLPRLYS----------------DAESQTD 285

  Fly   312 ILANADNNVQFASEKL-ISLGY--TKRDMQQPHRPNNRPPDLNQDQEAGGDQSGVHIPLRPKEYT 373
            |.|...::....:||: :||.|  .||.:     .|........|.||   ..|:..|.|.:...
Zfish   286 IPAQFVSSSNKLAEKVRLSLKYEEAKRRI-----ANIEVQIAKLDSEA---WPGLLDPERDRLIL 342

  Fly   374 EEEKTKMQTLLKE--------KYPQIAERIILMALESVNYAEDRATQILQIVQDED--------- 421
            ..||   :.||||        :.|..||:|     ||   .:.|..:.||..:|..
Zfish   343 INEK---EELLKELQYVRPCKRAPNEAEKI-----ES---EKKRLEKDLQAARDNQSKALTERLR 396

  Fly   422 ---------EQREQKQAPMNPKHLDLKK--------TTGTEQIDGANEKDSLPAVVEPTTSS--- 466
                     ::.|:.....:..|..||.        ::|:.:....:.:.||......:|||
Zfish   397 LHYRRNKLVKELEETVRVASSLHTQLKSLSASTLSCSSGSSRGSLTSSRGSLANSSLGSTSSLSF 461

  Fly   467 ------KPK---PPHKRHI------------LPSINVTT----------------PST-FTTQII 493
                  :|:   |..:..:            .||.::||                |.. ..||::
Zfish   462 TDVYLEQPELGDPDFQNKLDSILQEGSTSGYRPSSSITTIHENEVSSSSVQIGGGPGVGQRTQVL 526

  Fly   494 LAQATPTPTPTAEEMKLETHLSSISSASSSHSYASPPQSPRIFQQSY------------------ 540
            ....||             |..:..|..||.|..|||.||.:.:.|:
Zfish   527 RLSETP-------------HSMNSLSPRSSLSSLSPPCSPLVTEASFLSGEVFSGPASQLDLDLQ 578

  Fly   541 ERLTTKSILAKSGHNHFGHQSDTNNYSIDGYLHGSSNASSYSSYSASMTSSSLVSSAQSNSSSIA 605
            .||....:..........:| |....||.. :..|.:|.:.:..|...:..:.|:||.|:.|...
Zfish   579 TRLMELRLEEDQQQGQLNYQ-DNKQESIMA-VESSKDAVTQTRGSGPGSKKAGVTSAVSDESVAG 641

  Fly   606 ---------RRP--------AFESRARTKTDSLKHRQHSLGNSHNSESAEFQSIIERMASLGPNS 653
                     :||        ||:..:...:..:|     ||..:..:...|...:.::::.   |
Zfish   642 DSGVYEPSEKRPGLPVEQLLAFDDGSSASSAQIK-----LGLKYEVKEKRFTVFVMQLSNY---S 698

  Fly   654 QLSKGADENLLLADYVTWNGPNTKLLQK---QITQGP-----------NASLLTDRTYK------ 698
            .||..|::|:.:...|.......:.|.:   .:.|.|           :::.|..:|.:
Zfish   699 ALSLPANQNIYVRVVVLPCSETVRCLFRTHCALPQEPVELKEAFSLQVSSTALRQKTLRIDVCTT 763

  Fly   699 PRGGKSELCKGPQSGLA 715
            .:.|:.....|.|..||
Zfish   764 SKSGREHCLAGAQISLA 780

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10508	NP_001246859.1	CUE	291..327	CDD:270465	6/35 (17%)
wwc1	XP_689275.5	WW	9..39	CDD:238122
		WW	55..84	CDD:278809	13/29 (45%)
		C2_Kibra	672..795	CDD:176062	20/117 (17%)
		PHA03281	902..>1102	CDD:165538

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR14791
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100