Protein Alignment CG10510 and DRC2

DIOPT Version :10

• Sequence 1: NP_649291.2
• Gene: CG10510 / 40341
• FlyBaseID: FBgn0037059
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: NP_149115.2
• Gene: DRC2 / 85478
• HGNCID: 29937
• Length: 484
• Species: Homo sapiens
• Alignment Length: 487
• Identity: 104/487 - (21%)
• Similarity: 212/487 - (43%)
• Gaps: 104/487 - (21%)

  Fly    40 KKEAKRLAMIEEKRLIM-RDALMRELEMGKHME----------------------EKGNEEWHEM 81
            |::..:..:.:||:|:: :..|:.|.||.|..|                      .|.|.:|..:
Human     4 KEKMAKTPLSDEKQLLLFQQKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALNLNKINTQWRTV 68

  Fly    82 CREIKIKELNEEMRAWGERSERNIQAKNDHIKMLLDDMAQTQDQHVRCYSKTVELIDHIRDCFHV 146
            .||:|.:||::::....:..||.:..|::.||.|..|:::.::|:.......:..:|.:......
Human    69 LREVKTRELHKDIEILSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHALRSHLHNVDQLLALQRH 133

  Fly   147 MLGGVKSMYDQQADEMLRDYYEEVRRRT------EEVEAMKTNSENIIHATNITTRDQLKEDYTI 205
            .|..::..|:.:.:.:.:::  |..|:|      :|:..:    ::|..|..   ::.:..:|..
Human   134 RLSLLEESYNMELEALTKEF--ETERKTIIDQHEKEIHYL----QDIFMAME---QNYIDSEYES 189

  Fly   206 YLEQR---DDRVNTEIENRFKIRDQIVRRMTHMQQQLNDFVESLR-STELDAHKYEKIHWLTERQ 266
            .||.:   :|..|..:|.:..:|..:..|:..:.::..|.:::.. :||             :|:
Human   190 KLEFQSMWNDLKNMNLEEKHFLRLHLENRVEDLWRKFQDVLKNYTDATE-------------DRK 241

  Fly   267 AAFMEESRKLNAEESKYINMQAELQREMVR--MDA-----------------ENNSTLNDLRLEF 312
            |||  |:.::..|:|   :.:.|:|.:.::  .||                 ||....||..|..
Human   242 AAF--ETLQVKDEKS---SKEIEVQMKKIQKLQDAITISKGKIMIHSRESEDENRYIRNDKELVL 301

  Fly   313 QYFTNVRKKIELNQEMDREITHEKLRILTGECYELTKQMEKHVKSGELLLALSITCRKLQTESEK 377
            ...    :|::..:...|..:.:.|..||.|.....|.:.|.|..||.:|.|:..|||.:||.||
Human   302 VQL----RKLKAQRTQARAASQKNLVRLTLESNATLKALRKIVDKGEKILKLAEICRKFETEEEK 362

  Fly   378 VILGGEVFDETEVDVDEYFKLQTLNLKDHVDMTEEELVELNK------SLRNFWRRQAMAEAQNL 436
            |:    .|..:.:...|...:|..||:   ::||    ||.|      .:.|||:|....:.:.|
Human   363 VL----PFYSSVLTPKEQEGIQKNNLE---ELTE----ELTKVMVDYIGMENFWKRYNKVKLEQL 416

  Fly   437 LMLEEKRRLTEDNQRLIDFIK----SMSVTED 464
            .:...:.:|.:.|.:|.:.:|    .:||:::
Human   417 SLQHRRAQLLDINGKLREMLKQYLDGISVSDE 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10510	NP_649291.2	NYD-SP28	50..137	CDD:464307	25/109 (23%)
DRC2	NP_149115.2	NYD-SP28	27..124	CDD:464307	21/96 (22%)