DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment park and ARI12

DIOPT Version :9

Sequence 1:	NP_730600.1	Gene:	park / 40336	FlyBaseID:	FBgn0041100	Length:	482	Species:	Drosophila melanogaster
Sequence 2:	NP_001184919.1	Gene:	ARI12 / 837098	AraportID:	AT1G05880	Length:	496	Species:	Arabidopsis thaliana

Alignment Length:	405	Identity:	87/405 - (21%)
Similarity:	137/405 - (33%)	Gaps:	140/405 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   112 SATLEEEEPSLSDEASKPLNETLLDLQL--ESEER--LNITDEERVRAKAHF-------FVHCSQ 165
            ::.:..|..:.:||:.  :|..|.|.|.  :|.:|  ..:..||.:||....       |...|:
plant     4 NSVIGSEVDAEADESY--VNAALEDGQTGKKSVQRNYATVLTEEDIRALMEIDVQSVSDFTSLSK 66

  Fly   166 CDK---LCNGKLRVRCALCK---GGAFTVHRDPECWDDVLKSRRIPGHCESLEVACVDNAAGDPP 224
            .:.   |.:.:..|.| :||   .||.:|.      |.|          ..||:        |||
plant    67 AEATLLLSHLRWNVDC-ICKQWSAGAQSVR------DSV----------GLLEL--------DPP 106

  Fly   225 FAEFFFKCAEHVSGGEKDFAAPLNLIKNNIKNVPCLACTDVSDTVLVFPCASQHVTCIDCFRHYC 289
            ..:..:.|.   :.||          .:..||:..::|              .|..|..|:..:.
plant   107 SDDNEYFCG---ACGE----------SHPHKNLASVSC--------------GHRICTRCWTSHI 144

  Fly   290 RSRLGERQFMPHPDFGYTLPCP------AGCEHSF-IEEIHHFKLLTREEYDRYQRFATEEYV-- 345
            ...:.|:   |..::...|.||      |.|..|. ::.|..|  .::.|...|.::....||
plant   145 NKIISEK---PAAEWNLWLKCPVRVGLHASCPASVGLDTIERF--ASKREKFNYNQYLLRSYVDN 204

  Fly   346 --------LQAGGVLCP---QPGCGMGLLVEPDCRKVTCQNGCGYVFCRNCLQGYHIGECLPEGT 399
                    :|  |..|.   .||.|...:   .|.::.       .||.||.:..|
plant   205 RETMKWHPIQ--GSRCAIDLSPGSGNASV---SCHRLV-------RFCWNCREDAH--------- 248

  Fly   400 GASATNSCEYTVDPNRAAEARWDEASNVTIKVSTKPCPKC--RTPTERDGGCMHMVCTRAGCGFE 462
                     ..||...|  |:|       :..:..|||||  |.|..:|.. :.|.|  ..|.:.
plant   249 ---------SPVDCKTA--AKW-------LLENAVPCPKCKLRIPRNQDNS-LKMKC--LPCNYV 292

  Fly   463 WCWVCQTEWTRDCMG 477
            :||.|..:|..|..|
plant   293 FCWFCHVDWIEDMEG 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
park	NP_730600.1	UBQ	30..97	CDD:214563
		parkin_N	32..101	CDD:176393
		IBR	334..390	CDD:214763	14/68 (21%)
		IBR	<435..471	CDD:279784	14/37 (38%)
ARI12	NP_001184919.1	Zn_Tnp_IS91	<111..>139	CDD:291017	8/54 (15%)
		IBR	193..253	CDD:214763	16/89 (18%)
		IBR	<266..301	CDD:303000	14/37 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11685
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010