DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment park and ARI10

DIOPT Version :9

Sequence 1:	NP_730600.1	Gene:	park / 40336	FlyBaseID:	FBgn0041100	Length:	482	Species:	Drosophila melanogaster
Sequence 2:	NP_180735.1	Gene:	ARI10 / 817733	AraportID:	AT2G31760	Length:	514	Species:	Arabidopsis thaliana

Alignment Length:	354	Identity:	84/354 - (23%)
Similarity:	129/354 - (36%)	Gaps:	112/354 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   132 ETLLDLQLESEERLN----ITDEERVRAKAHFFVHCSQCDKLCNGKLRVRCALCKGGAFTVHRDP 192
            |.:|.||.:..||::    ::..|.:....|:        ..|..||                :.
plant    49 EEILKLQRDDIERVSTILFLSQVEAIVLLLHY--------HWCVSKL----------------ED 89

  Fly   193 ECWDDVLKSRRIPGHCESLEVACVDNAAGDPPFAEFFFKCAEHVSGGEKDFAAPLNLIKNNIKNV 257
            |.:.|..:.|:..|   .|:...||                  |:|.|.|....:.......|.:
plant    90 EWFTDEERIRKTVG---ILKEPVVD------------------VNGTEVDIQCGICFESYTRKEI 133

  Fly   258 PCLACTDVSDTVLVFPCASQHVTCIDCFRHYCRSRLGE-----RQFMPHPDFGYTLPCPAGCEHS 317
            ..::|              .|..|..|:..|..:::.:     |...|.|.      |.|.....
plant   134 ASVSC--------------GHPYCKTCWTGYITTKIEDGPGCLRVKCPEPS------CYAVVGQD 178

  Fly   318 FIEEIHHFKLLTREEYDRYQRFATEEYVLQAGGVL--CPQPGCGMGL-LVEPDCRKVTCQNGCGY 379
            .|:|:     ..:::.|:|.|:....|| :.|..:  ||.|||...: ..|.....|.|.  |.|
plant   179 MIDEV-----TEKKDKDKYYRYFLRSYV-EDGKKMKWCPSPGCECAVEFGESSGYDVACL--CSY 235

  Fly   380 VFCRNCLQGYHIGECLPEGTGASATNSCEYTVDPNRAAEARW-----DEASNVT-IKVSTKPCPK 438
            .||.||.:..|            :...|| ||       ::|     ||:.|.. |..::|||||
plant   236 RFCWNCSEDAH------------SPVDCE-TV-------SKWIFKNQDESENKNWILANSKPCPK 280

  Fly   439 CRTPTERDGGCMHMVCTRAGCGFEWCWVC 467
            |:.|.|:..||.||.|: |.||..:||:|
plant   281 CKRPIEKSHGCNHMTCS-ASCGHRFCWIC 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
park	NP_730600.1	UBQ	30..97	CDD:214563
		parkin_N	32..101	CDD:176393
		IBR	334..390	CDD:214763	20/58 (34%)
		IBR	<435..471	CDD:279784	18/33 (55%)
ARI10	NP_180735.1	RING-HC_RBR_TRIAD1_like	121..171	CDD:319537	9/69 (13%)
		IBR	190..251	CDD:214763	21/75 (28%)
		IBR	<273..312	CDD:396187	19/37 (51%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11685
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010