DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment park and rnf217

DIOPT Version :9

Sequence 1:	NP_730600.1	Gene:	park / 40336	FlyBaseID:	FBgn0041100	Length:	482	Species:	Drosophila melanogaster
Sequence 2:	NP_001076322.1	Gene:	rnf217 / 567287	ZFINID:	ZDB-GENE-060503-400	Length:	543	Species:	Danio rerio

Alignment Length:	435	Identity:	92/435 - (21%)
Similarity:	156/435 - (35%)	Gaps:	127/435 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 RPPVQRQKIQSATL----------EEEEPSLSDEASKPLNETLLDLQLES-EERL---------- 145
            |..::|:.|::..:          :.|:|...::....:|  |.||..|: :|||
Zfish    75 REHIERENIRAVDILRRNFGSTIRDTEDPKNLEKVGNDIN--LNDLDHENDDERLQCSTINLQQD 137

  Fly   146 ------------------NI---TDEERVRAKAHFF--VHCSQCDKLCNGKLRV----------R 177
                              ||   :.|:..::|.|.:  |:|     :.|...|:          .
Zfish   138 IESNPELGNPDGNHHIDYNIDLKSGEDPSQSKEHVYCTVYC-----IANDNYRIPVQKTTSNHET 197

  Fly   178 CALCKGGAFTVHRDPECWDDVLKSRRIPGHCESLEVACVDNAAGDPPFAEFFFKCAEHVSGGEKD 242
            .:.....:.:....|:..  ||.|..:|    :||   :||   ..|:...:......|||....
Zfish   198 SSSSSSSSSSSSSSPDVL--VLPSTDLP----NLE---LDN---HDPYPVPYTVSDLMVSGIHSS 250

  Fly   243 FAAPLNLIKNNIKNV-PCLACTDVSDTVLVFPCASQHVTCIDCFRHYCRSRLGERQFMPHPDFGY 306
            :.|     .|::..| .|..|.| ...::...|..:.| |.:|.:.|..|::       |....:
Zfish   251 YNA-----DNSLSVVLTCRICLD-DKQIMPLHCCKKAV-CEECLKRYIISQV-------HVGRAH 301

  Fly   307 TLPCPAGCEHSFIEE---IHHFKLLTREEYDRYQRFATEEYVLQAGGVLCPQPGCGM-----GLL 363
             |.||......|:||   |.|   ||.||..:|:.| .|...|.:....|||  |.:     |..
Zfish   302 -LVCPITECSGFLEENLVISH---LTSEELAKYKYF-LELSQLDSSTKPCPQ--CSLFTSLRGRS 359

  Fly   364 VEPDCR-----KVTCQNGCGYVFCRNCLQGYHIG-ECLPEGTGASATNSCEYTVDPNRAAEARWD 422
            .:...:     |:.|.. |.:|:|..|...:|.| :|.....|..........::..:.
Zfish   360 QQSSTKSEHKYKIQCTK-CQFVWCFKCHSPWHEGLKCRDYRKGDKLLRHWASVIERGQR------ 417

  Fly   423 EASNVTIKVSTKPCPKCRTPTERDGGCMHMVCTRAGCGFEWCWVC 467
                     :.:.||:|:...:|..||.||.||:  |...:|:.|
Zfish   418 ---------NAQKCPRCKIHIQRTEGCDHMTCTQ--CSTNFCYRC 451

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
park	NP_730600.1	UBQ	30..97	CDD:214563
		parkin_N	32..101	CDD:176393
		IBR	334..390	CDD:214763	15/65 (23%)
		IBR	<435..471	CDD:279784	13/33 (39%)
rnf217	NP_001076322.1	IBR	328..395	CDD:214763	17/70 (24%)
rnf217	NP_001076322.1	IBR	<417..455	CDD:279784	13/52 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1140368at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920