Protein Alignment park and rnf19a

DIOPT Version :10

• Sequence 1: NP_730600.1
• Gene: park / 40336
• FlyBaseID: FBgn0041100
• Length: 482
• Species: Drosophila melanogaster
• Sequence 2: NP_001313624.1
• Gene: rnf19a / 557995
• ZFINID: ZDB-GENE-030131-9414
• Length: 913
• Species: Danio rerio
• Alignment Length: 471
• Identity: 106/471 - (22%)
• Similarity: 166/471 - (35%)
• Gaps: 127/471 - (26%)

  Fly    51 DIKNVKELVAPQLGLQPDDLKIIFAGKELSDATTIEQCDL-GQQSVLHAIRLRPP---VQRQKIQ 111
            |:|:       |:.:||.|.|:          |.:.|.:| |.:..|  ....||   ..|..::
Zfish     8 DLKD-------QVEIQPGDSKL----------TRVSQLELPGSREQL--AESSPPCLNTSRSPLK 53

  Fly   112 S----ATLEEEEPSLSDEASKPLN-------------ETLLDLQLESEER--------------L 145
            :    .:|....||.|...|.|::             |..|..|.:..||              .
Zfish    54 TLSPLPSLSPPSPSSSSSPSLPVDTSQSFGNHSASFGEMSLHQQQQGSERDLPSAASSVSLPSVR 118

  Fly   146 NITDEERVRAKAHFFVHCSQCDKLCNGKLRVRCALCKG-----GAFTVHRDPECWDDVLKSRRIP 205
            ....:.|:..::.|...|.      :.|.|...||..|     ...:||.:
Zfish   119 KTPKKRRISLRSLFRRRCG------DPKSRKSRALAAGVDGIASVESVHSE-------------- 163

  Fly   206 GHCESLEVACVDNAAGDPPFAEFFFKCAEHVSGGEKDFAAPLNLIKNNIKNVP-CLACTDVSDTV 269
             .|:..:.|...:|||   .|.....|:.......:....||.|:::.....| .:.|
Zfish   164 -MCQQQDHASALSAAG---VAYTSSSCSSSSGSTSELLECPLCLLRHTRDRFPDIMTC------- 217

  Fly   270 LVFPCASQHVTCIDCFRHYCRSRLGERQFMPHPDFGYTLPCPAGCEHSFIEEIHHFKLLTREE-- 332
                   .|.:|.||.|.|.|..:.|.:        ..:.||. |...|  ..|..:::..:.
Zfish   218 -------HHRSCADCLRQYLRIEISESR--------VNISCPE-CSERF--NPHDIRMILNDRVL 264

  Fly   333 YDRYQRFATEEY-VLQAGGVLCPQPGCGMGLLVE--PDCRKVTC-QNGCGYVFCRNCLQGYHIGE 393
            .::|:.|....: |.......||.|.||..::..  ..|.|:|| ::|||..||.:|.|.:|
Zfish   265 MEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKITCGRDGCGTEFCYHCKQLWH--- 326

  Fly   394 CLPEGT--GASATNSCEYTVDPNRAAEARWDEASNVTIKVSTKPCPKCRTPTER--DGGCMHMVC 454
              |..|  .|....:....:.|.|::...:.:.|..... ..||||:|.....:  ||.|.||.|
Zfish   327 --PNQTCDAARQQRAQSLRLRPFRSSSLSYSQESGAAAD-DIKPCPRCAAYIIKMNDGSCNHMTC 388

  Fly   455 TRAGCGFEWCWVCQTE 470
              |.||.|:||:|..|
Zfish   389 --AVCGCEFCWLCMKE 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
park	NP_730600.1	Ubl_parkin	32..105	CDD:340496	14/57 (25%)
		RING0_parkin	159..250	CDD:412057	18/95 (19%)
		zf-RING_14	249..337	CDD:465601	16/90 (18%)
		BRcat_RBR_parkin	322..398	CDD:439001	22/81 (27%)
		Rcat_RBR_parkin	428..481	CDD:439018	19/45 (42%)
rnf19a	NP_001313624.1	RING-HC_RBR_RNF19A	205..252	CDD:438431	14/71 (20%)
		BRcat_Rcat_RBR	258..340	CDD:459240	23/86 (27%)
		Rcat_RBR_RNF19	362..430	CDD:439016	19/44 (43%)