Protein Alignment park and pdr-1

DIOPT Version :10

• Sequence 1: NP_730600.1
• Gene: park / 40336
• FlyBaseID: FBgn0041100
• Length: 482
• Species: Drosophila melanogaster
• Sequence 2: NP_001370029.1
• Gene: pdr-1 / 176816
• WormBaseID: WBGene00003967
• Length: 386
• Species: Caenorhabditis elegans
• Alignment Length: 463
• Identity: 142/463 - (30%)
• Similarity: 207/463 - (44%)
• Gaps: 85/463 - (18%)

  Fly    26 LTHTLSIYV---KTNTGKTLTVNLEPQWDIKNVKELVAPQLGLQPDDLKIIFAGKELSDATTIEQ 87
            ::..:||.:   ||...:.||:|:....:|:::.:.|.....:..|:|:::|.||:||.:|.:.
 Worm     1 MSDEISILIQDRKTGQRRNLTLNINITGNIEDLTKDVEKLTEIPSDELEVVFCGKKLSKSTIMR- 64

  Fly    88 CDLGQQSVLHAIRLRPPVQRQKIQSATLEEEEPSLSDEASKPLNETLLDLQLESEERLNITDEER 152
             ||........:.|||.........||..:                             ||.:..
 Worm    65 -DLSLTPATQIMLLRPKFNSHNENGATTAK-----------------------------ITTDSS 99

  Fly   153 VRAKAHFFVHCSQCDKLCNGKLRVRCALCKGGAFTVHRDPECWDDVLKSRRIPGHCESLEVACVD 217
            :...  |:|.|..||.:..|||||.|..|...:..|..:|:.|.|||||:|||..||.   .|..
 Worm   100 ILGS--FYVWCKNCDDVKRGKLRVYCQKCSSTSVLVKSEPQNWSDVLKSKRIPAVCEE---CCTP 159

  Fly   218 NAAGDPPFAEFFFKCAEHVSGGEKDFAAPLNLIKNNIKNVPCLACTDVSDTVLVFPCASQHVTCI 282
            ..     ||||.|||.     ...|.||.|..::.|.:...|..| |..:.| :|.....|:||.
 Worm   160 GL-----FAEFKFKCL-----ACNDPAAALTHVRGNWQMTECCVC-DGKEKV-IFDLGCNHITCQ 212

  Fly   283 DCFRHYCRSRLGERQFMPHPDFGYTLPCP-AGCEHSFIEEIHHFKLLTREEYDRYQRFATEEYV- 345
            .|||.|..|:|....|:..|..|:|:.|| .|| :..::::|||.::.:..|..|||.|||..:
 Worm   213 FCFRDYLLSQLERFGFVNQPPHGFTIFCPYPGC-NRVVQDVHHFHIMGQTSYSEYQRKATERLIA 276

  Fly   346 LQAGGVLCPQPGCGMGLLVEP--DCRKVTCQNGCGYVFCRNCLQGYHIGECLPEGTGASATNSCE 408
            :...||.||...||.....||  |..:..|.: |.:.|||.|.:...:  |..|
 Worm   277 VDDKGVTCPNVSCGQSFFWEPYDDDGRSQCPD-CFFSFCRKCFERNCV--CQSE----------- 327

  Fly   409 YTVDPNRAAEARWDEASNVTIKVSTKPCPKCRTPTERDGGCMHMVCTRAGCGFEWCWVCQTEWTR 473
                         |:.:..||..:|:.||||...|||:|||.|:.||  .||.:||:.|:|||..
 Worm   328 -------------DDLTRTTIDATTRRCPKCHVATERNGGCAHIHCT--SCGMDWCFKCKTEWKE 377

  Fly   474 DCMGAHWF 481
            :|...|||
 Worm   378 ECQWDHWF 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
park	NP_730600.1	Ubl_parkin	32..105	CDD:340496	21/75 (28%)
		RING0_parkin	159..250	CDD:412057	37/90 (41%)
		zf-RING_14	249..337	CDD:465601	27/88 (31%)
		BRcat_RBR_parkin	322..398	CDD:439001	26/78 (33%)
		Rcat_RBR_parkin	428..481	CDD:439018	26/52 (50%)
pdr-1	NP_001370029.1	Ubl_ubiquitin_like	13..77	CDD:340559	17/65 (26%)
		RING0_parkin	104..182	CDD:412057	37/90 (41%)
		zf-RING_14	182..267	CDD:465601	27/87 (31%)
		BRcat_Rcat_RBR	252..319	CDD:459240	25/67 (37%)
		Rcat_RBR_parkin	333..385	CDD:439018	26/53 (49%)