| Sequence 1: | NP_730600.1 | Gene: | park / 40336 | FlyBaseID: | FBgn0041100 | Length: | 482 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_699172.2 | Gene: | RNF19B / 127544 | HGNCID: | 26886 | Length: | 732 | Species: | Homo sapiens |
| Alignment Length: | 280 | Identity: | 75/280 - (26%) |
|---|---|---|---|
| Similarity: | 108/280 - (38%) | Gaps: | 81/280 - (28%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 219 AAGDPPFAEFFFKCAEHVSGGEKDFAAPLNLIKNNIKNVP-CLACTDVSDTVLVFPCASQHVTCI 282
Fly 283 DCFRHYCRSRLGERQFMPHPDFGYTLPCPAGCEHSFIEEIHHFKLLTREE--YDRYQRFATEEYV 345
Fly 346 LQAGGV-LCPQPGCGMGLLVE--PDCRKVTCQ-NGCGYVFCRNCLQGYHIGECLPEGTGASATNS 406
Fly 407 CEYTVDPNRAAE-ARWDEASNVTIKVST------------------KPCPKCRTPTER--DGGCM 450
Fly 451 HMVCTRAGCGFEWCWVCQTE 470 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| park | NP_730600.1 | Ubl_parkin | 32..105 | CDD:340496 | |
| RING0_parkin | 159..250 | CDD:412057 | 9/30 (30%) | ||
| zf-RING_14 | 249..337 | CDD:465601 | 20/90 (22%) | ||
| BRcat_RBR_parkin | 322..398 | CDD:439001 | 22/81 (27%) | ||
| Rcat_RBR_parkin | 428..481 | CDD:439018 | 22/63 (35%) | ||
| RNF19B | NP_699172.2 | Required for ubiquitin ligase activity and for protection against staurosporin-induced cell death. /evidence=ECO:0000269|PubMed:27485036 | 1..318 | 73/275 (27%) | |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..112 | 6/18 (33%) | |||
| TRIAD supradomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU01221 | 115..337 | 68/258 (26%) | |||
| RING-HC_RBR_RNF19B | 116..179 | CDD:438432 | 21/87 (24%) | ||
| BRcat-RBR_RNF19B | 184..258 | CDD:439024 | 23/95 (24%) | ||
| Rcat_RBR_RNF19 | 281..349 | CDD:439016 | 19/43 (44%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 618..732 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||