DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG42337 and ARID4B

DIOPT Version :9

Sequence 1:NP_001246858.1 Gene:CG42337 / 40335 FlyBaseID:FBgn0259239 Length:610 Species:Drosophila melanogaster
Sequence 2:NP_001193723.1 Gene:ARID4B / 51742 HGNCID:15550 Length:1312 Species:Homo sapiens


Alignment Length:402 Identity:76/402 - (18%)
Similarity:148/402 - (36%) Gaps:108/402 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   208 DVEVEAVAESPAQRLTTSPPMISATGTDSGISNCSTRARSDSSQSTPVYSGEYPVNMSVESASCV 272
            |.:.||.|         |||   ....:.|::..|.:..::....:|....|.|..::|:|.   
Human   946 DSDTEAAA---------SPP---HPAPEEGVAEESLQTVAEEESCSPSVELEKPPPVNVDSK--- 995

  Fly   273 PYHCPADARDYEEEEHQ--------------PPVTAEVRRADTPLDITDDISATSPVAADEVKPT 323
                |.:.:..|..:.:              ||.|.|   :.:.:.:|:.....|.|...|  |.
Human   996 ----PIEEKTVEVNDRKAEFPSSGSNSVLNTPPTTPE---SPSSVTVTEGSRQQSSVTVSE--PL 1051

  Fly   324 APTSSQV---AKSAETNLQPDSAASLDVPTTPQDTSGDP------ITEAADERPEHARQQQHP-- 377
            ||...:|   ....::.::.||.|. ::.....:.:..|      ::.::..:||    .:||  
Human  1052 APNQEEVRSIKSETDSTIEVDSVAG-ELQDLQSEGNSSPAGFDASVSSSSSNQPE----PEHPEK 1111

  Fly   378 ----------VTNNWSPTTRRPRTPPAP--QNSPIGFGQNASVPPALAHLLQQQQQQQLQLQQQQ 430
                      .....|.:.::.|:..|.  .|...|.|.|:|            ..::|...:..
Human  1112 ACTGQKRVKDAQGGGSSSKKQKRSHKATVVNNKKKGKGTNSS------------DSEELSAGESI 1164

  Fly   431 QQQQVGNLKRCATSGKNRSSHNRII-----EC----DLIPSKKSKRKSVKK------QAGEIENM 480
            .:.|  .:|..:|..|:.|:.:...     :|    |..|..|.....:.|      |..::|||
Human  1165 TKSQ--PVKSVSTGMKSHSTKSPARTQSPGKCGKNGDKDPDLKEPSNRLPKVYKWSFQMSDLENM 1227

  Fly   481 EAVE--PIVREQIRDIKPLPGFLQAFGSTEIGRFSERFLQTPESLVERLAEEYAGSAPNNCPSHS 543
            .:.|  .|::|::::|:  ..:|..  .:|:.....|    .:.|.::..|..|.|:.::.||.|
Human  1228 TSAERITILQEKLQEIR--KHYLSL--KSEVASIDRR----RKRLKKKERESAATSSSSSSPSSS 1284

  Fly   544 AGGYIESPAMAT 555
            :   |.:..|.|
Human  1285 S---ITAAVMLT 1293

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG42337NP_001246858.1 None
ARID4BNP_001193723.1 TUDOR 58..113 CDD:197660
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 124..166
RBB1NT 170..262 CDD:285392
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 266..306
ARID 311..394 CDD:198082
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 458..577
Antigenic epitope 465..473
Tudor-knot 571..624 CDD:288553
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 635..680
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 708..894
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 909..1212 54/308 (18%)
Antigenic epitope 1130..1137 1/6 (17%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1252..1288 10/42 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG2744
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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