Protein Alignment CG42337 and ARID3A

DIOPT Version :9

• Sequence 1: NP_001246858.1
• Gene: CG42337 / 40335
• FlyBaseID: FBgn0259239
• Length: 610
• Species: Drosophila melanogaster
• Sequence 2: NP_005215.1
• Gene: ARID3A / 1820
• HGNCID: 3031
• Length: 593
• Species: Homo sapiens
• Alignment Length: 485
• Identity: 92/485 - (18%)
• Similarity: 153/485 - (31%)
• Gaps: 135/485 - (27%)

  Fly   113 QQSQPGYEPPPPLPYSSSASY--QSRGFGAFAG------------PTPHYAPPGRSSTPAPNRTV 163
            ::.:.|..||.|....::|.:  :::...||.|            |.|..|.||.::..||.  :
Human   153 EEDEEGLGPPGPASLGTTALFPRKAQPPQAFRGDGVPRVLGGQERPGPGPAHPGGAAHVAPQ--L 215

  Fly   164 LPPSYLEPLRSYSAEQQHLSQQQHLSQQQLQHHPLPGTPKLEDPDVEVEAVAE---SPAQRLTTS 225
            .||.:    ..::.|:|.         :||  :.|.|.||.::...::.:..:   :|..|:...
Human   216 QPPDH----GDWTYEEQF---------KQL--YELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIM 265

  Fly   226 PP------MISATGTDSG----ISNCSTRARSDSSQSTPVYSGEYPVNMSVESAS---------- 270
            ..      |:....|:.|    :.|...........:.|.         |:.||:
Human   266 AKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPT---------SITSAAFTLRTQYMKY 321

  Fly   271 CVPYHCPADARDYEEEEHQPPVTAEVRRADTPLDITDDISATSPVAADEV--KPTAPTSSQVAKS 333
            ..||.|  :.|...............||..........:.|.||..|..:  .|..|.|| :..:
Human   322 LYPYEC--EKRGLSNPNELQAAIDSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSS-LGLA 383

  Fly   334 AETNLQPDSAASLDVPTTPQDTSGDPITEAADERPEHARQQQHPVTNNWSPTTRRPRTPPAPQNS 398
            |.||                   |..||.|    |:..:::...:     |.|...|.|.:....
Human   384 ASTN-------------------GSSITPA----PKIKKEEDSAI-----PITVPGRLPVSLAGH 420

  Fly   399 PIGFGQNASVPPALAHLLQQQQQQQL-QLQQQQQQQQVGNLKRCATSGKNRSSHNRIIECDLIPS 462
            |:...|.|:|..|.|......|...| ||:::.:..:....|....:.:.:....|.::.:.:..
Human   421 PVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAM 485

  Fly   463 KKSKRKSVK--KQAGEIENMEAVEPIVREQIRDIKPLPGFLQAFGSTEIGRFSE---------RF 516
            ......|::  .||.|.....||.            |.|   ..||..|....|         .|
Human   486 AAQLPMSIRINSQASESRQDSAVN------------LTG---TNGSNSISMSVEINGIMYTGVLF 535

  Fly   517 LQTPESLVERLAEEYAGSAPNNCPSHSAGG 546
            .|.|            ...|.:.|:...||
Human   536 AQPP------------APTPTSAPNKGGGG 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42337	NP_001246858.1	None
ARID3A	NP_005215.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	14..222		17/74 (23%)
		Acidic	119..156		0/2 (0%)
		BRIGHT	239..331	CDD:128777	15/102 (15%)
		Important for nuclear localization. /evidence=ECO:0000250	445..488		5/42 (12%)
		Homodimerization	490..513		8/37 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	497..516		7/33 (21%)
		Important for cytoplasmic localization. /evidence=ECO:0000250	537..557		6/29 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	539..593		5/27 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2744
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900