DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ac78C and CG14877

DIOPT Version :9

Sequence 1:	NP_001262138.1	Gene:	Ac78C / 40333	FlyBaseID:	FBgn0024150	Length:	1727	Species:	Drosophila melanogaster
Sequence 2:	NP_650507.1	Gene:	CG14877 / 41929	FlyBaseID:	FBgn0038380	Length:	254	Species:	Drosophila melanogaster

Alignment Length:	289	Identity:	51/289 - (17%)
Similarity:	98/289 - (33%)	Gaps:	107/289 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly  1323 YHARLVEVTSRLDFIWKEQAERELTNMKSNRALNDTLIKNILPDHVATYYLS-DEHTDELYSKMH 1386
            |.|.|..|...|     :.||:::.:            |:::|.|:...:|: |...|.....:.
  Fly    54 YQASLPRVLPIL-----KVAEQQIRS------------KSLIPSHIDFEWLAHDTKCDASLGVIK 101

  Fly  1387 NLCGVMFASIPNFQDFYSEDIDNGKACIRILNEIICDFDELLEEPRFASVEKI----KTVGATYM 1447
            .:.|::                  |.|.:::...:||:.       .|:|.:|    .:.|...:
  Fly   102 AMDGII------------------KQCAQVIFGPVCDYS-------LAAVSRITKYFNSQGTPLI 141

  Fly  1448 AAAGLNHEHLRLRGETSEDSVCDLVEFAFAMKQKLEEINGDAFNNFQLRVGICSGPLVSGVIGAR 1512
            :..|..::                      .:||..:.|.:.:  ..||.|:.|...:|.:
  Fly   142 SVGGSTYD----------------------FEQKKTDCNDEFY--MLLRTGMLSFETISEL---- 178

  Fly  1513 KPVYDIWGNTVNVASRMDSTGENWRVQVPENTAELLCSRGYTCVKRGEIAVKGKGMMTTFYVHPK 1577
                     |:||..|     .||...:            :...:.|:.:|.|   |.|.::..|
  Fly   179 ---------TINVMKR-----HNWSHSI------------FYYERDGQRSVAG---MHTCFLMMK 214

  Fly  1578 GISESQLISPVRMPAGIPLAQTPNLQRQT 1606
            .:.: |:.:.....|..||  .|||..:|
  Fly   215 SLGK-QMRNENMTFAQFPL--EPNLTNRT 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ac78C	NP_001262138.1	AC_N	<288..551	CDD:292831
		CYCc	526..729	CDD:214485
		Guanylate_cyc	566..753	CDD:278633
		DUF1053	929..1020	CDD:283888
		CYCc	1353..1554	CDD:214485	30/205 (15%)
		Guanylate_cyc	1381..1576	CDD:278633	29/198 (15%)
CG14877	NP_650507.1	Periplasmic_Binding_Protein_Type_1	46..>241	CDD:299141	51/289 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900