DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ac78C and CG31183

DIOPT Version :9

Sequence 1:	NP_001262138.1	Gene:	Ac78C / 40333	FlyBaseID:	FBgn0024150	Length:	1727	Species:	Drosophila melanogaster
Sequence 2:	NP_001287342.1	Gene:	CG31183 / 41927	FlyBaseID:	FBgn0051183	Length:	1417	Species:	Drosophila melanogaster

Alignment Length:	382	Identity:	99/382 - (25%)
Similarity:	172/382 - (45%)	Gaps:	66/382 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly  1339 KEQAERELTNMKSNRALNDTLIKNILPDHVATYYLSDEHTDELYSKMHNLCGVMFASIPNFQDFY 1403
            :|..|....:....:...:.|:..:||..||...:|.:   .:.::..:...:.|:.|..|....
  Fly   905 EELVEERTQDYHEEKKKCEKLLYQLLPQSVAAQLISGQ---PVVAETFDQVTIYFSDIVGFTAIS 966

  Fly  1404 SEDIDNGKACIRILNEIICDFDELLEEPRFASVEKIKTVGATYMAAAGL----NHEHLRLRGETS 1464
            :|  ......::.||::...||.::|.   ..|.|::|:|..||..:||    .::|.|
  Fly   967 AE--STPMQVVQFLNDLYTCFDSIVEN---FDVYKVETIGDAYMVVSGLPIRNGNQHAR------ 1020

  Fly  1465 EDSVCDLVEFAFAMKQKLEEINGDAFNNF----------QLRVGICSGPLVSGVIGARKPVYDIW 1519
                 ::...|.|:.        :|.:||          :||:|:.:|..|:||:|.:.|.|.::
  Fly  1021 -----EIARLALALL--------EAVHNFRIHHRPEDRLKLRIGLHTGACVAGVVGLKMPRYCLF 1072

  Fly  1520 GNTVNVASRMDSTGENWRVQVPENTAELLCSRG-YTCVKRGEIAVKGKGMMTTFYVHPKGISESQ 1583
            |:|||.||||:|.||..::.:.|.|.|.|...| :...:||.:.:||||.|.|:::..:....:.
  Fly  1073 GDTVNTASRMESNGEALKIHISETTKEALDEFGTFVTTRRGFVPMKGKGEMLTYWLEGEVPRPNS 1137

  Fly  1584 LISPVRMPAGIPLAQTPNL---QRQTSH--HGSFSAVVFGMLQASKRSTAIAGTPTGTP---SPQ 1640
            ||||.:    :.|.:..:|   ||..||  |..:|.:|...........|||..|..:|   ||.
  Fly  1138 LISPSK----LMLTRRSSLKQPQRSQSHNLHKQYSELVVASPPPQLPPPAIALPPPPSPSKDSPN 1198

  Fly  1641 IRRGHRGSTFSSVRLS------QKS-----TTVNPVRRNTTRVRGRSYRQKKSSSNN 1686
            :|...:.|: ||.:|:      .|:     .|....:||......||.|..:.:|::
  Fly  1199 LRVKRKISS-SSPKLNGGGFDYHKTENHYLDTAAAAQRNCDIYSSRSLRDMEETSDS 1254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ac78C	NP_001262138.1	AC_N	<288..551	CDD:292831
		CYCc	526..729	CDD:214485
		Guanylate_cyc	566..753	CDD:278633
		DUF1053	929..1020	CDD:283888
		CYCc	1353..1554	CDD:214485	56/215 (26%)
		Guanylate_cyc	1381..1576	CDD:278633	58/209 (28%)
CG31183	NP_001287342.1	PBP1_NPR_like	88..498	CDD:107368
		ANF_receptor	108..473	CDD:279440
		PK_GC-A_B	589..883	CDD:270944
		Pkinase_Tyr	613..877	CDD:285015
		HNOBA	<893..938	CDD:285003	7/32 (22%)
		CYCc	917..1108	CDD:214485	56/217 (26%)
		Guanylate_cyc	944..1130	CDD:278633	58/209 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810