DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ac78C and CG33958

DIOPT Version :9

Sequence 1:	NP_001262138.1	Gene:	Ac78C / 40333	FlyBaseID:	FBgn0024150	Length:	1727	Species:	Drosophila melanogaster
Sequence 2:	NP_001033958.1	Gene:	CG33958 / 37088	FlyBaseID:	FBgn0053958	Length:	710	Species:	Drosophila melanogaster

Alignment Length:	423	Identity:	110/423 - (26%)
Similarity:	199/423 - (47%)	Gaps:	84/423 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly  1185 EFV-RSTLNALTLNLTPPLPQSHRPYTLTTNGHSVSLSNLSYSDASVMQSSSDVEGQCAHPEY-- 1246
            ||: |..:|: |||..|.|...:...|.|...|     .......::::::.:|..:.:..||
  Fly   321 EFMAREMINS-TLNYAPMLKNMYTNITSTKKFH-----RAKQMGTTLLKNNPNVSNERSAIEYYE 379

  Fly  1247 LVFTWVLCLVSLATALKLYYLVKALMALAMVAFYTTLIMMKFGSGDSFSLVELSRL-GMPLGVQM 1310
            |:..:...|..|..||:  .|:|..:                    ..:|||..|. .:.:.:.:
  Fly   380 LMNNYTDDLRILQKALR--RLIKEYV--------------------DKTLVEADRKEAIGIAILV 422

  Fly  1311 LILLISFLVMVCYHARLVEVTSRLDFIWKEQAERELTNMKSNRALNDTLIKNILPDHVATYYLSD 1375
            ::|::|.:::|.  .:....|.:|..:...|..:||   |..:..:|:|:..:||..||   :..
  Fly   423 VVLIVSPVIIVL--VKNAAATIQLYALNLSQKAKEL---KREKRKSDSLLFQMLPPSVA---MQL 479

  Fly  1376 EHTDELYSKMHNLCGVMFASIPNFQDFYSEDIDNGKAC-----IRILNEIICDFDELLEEPRFAS 1435
            :.|.::.::::....:.|:.|..|.:..::       |     :..||.|...|||.:|   ...
  Fly   480 KQTQQVPAELYEAVTIYFSDIVGFTEIAAD-------CTPLEVVTFLNSIYRVFDERIE---CYD 534

  Fly  1436 VEKIKTVGATYMAAAGL----NHEHLRLRGETSE--DSVCDLVEFA--FAMKQKLEEINGDAFNN 1492
            |.|::|:|.:||.|:||    .::|:      ||  ....||::.:  |.:.:.     ||.|
  Fly   535 VYKVETIGDSYMVASGLPVKNGNKHI------SEIATMALDLLDASSVFRIPRA-----GDEF-- 586

  Fly  1493 FQLRVGICSGPLVSGVIGARKPVYDIWGNTVNVASRMDSTGENWRVQVPENTAELLCS-RGYTCV 1556
            .|:|.|:.:||:|:|::|.:.|.|.::|:|||.||||:||||..::.:.|...:.|.. .|:...
  Fly   587 VQIRCGVHTGPVVAGIVGTKMPRYCLFGDTVNTASRMESTGEAQKIHITEEMHDSLQQVGGFRTE 651

  Fly  1557 KRGEIAVKGKGMMTTFYVHPKGISESQLISPVR 1589
            .||.|.|||||:|:|:::..|.       .|||
  Fly   652 HRGLIDVKGKGLMSTYWLTCKD-------GPVR 677

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ac78C	NP_001262138.1	AC_N	<288..551	CDD:292831
		CYCc	526..729	CDD:214485
		Guanylate_cyc	566..753	CDD:278633
		DUF1053	929..1020	CDD:283888
		CYCc	1353..1554	CDD:214485	61/214 (29%)
		Guanylate_cyc	1381..1576	CDD:278633	64/208 (31%)
CG33958	NP_001033958.1	NIT	159..396	CDD:285564	19/80 (24%)
		HNOBA	<439..479	CDD:285003	12/45 (27%)
		CYCc	459..647	CDD:214485	60/213 (28%)
		Guanylate_cyc	485..669	CDD:278633	64/206 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810