Protein Alignment Ac78C and gcy-37

DIOPT Version :9

• Sequence 1: NP_001262138.1
• Gene: Ac78C / 40333
• FlyBaseID: FBgn0024150
• Length: 1727
• Species: Drosophila melanogaster
• Sequence 2: NP_500171.2
• Gene: gcy-37 / 191658
• WormBaseID: WBGene00001557
• Length: 708
• Species: Caenorhabditis elegans
• Alignment Length: 594
• Identity: 128/594 - (21%)
• Similarity: 215/594 - (36%)
• Gaps: 181/594 - (30%)

  Fly   244 GPKRRTESCSIFGNSNFEHDLESGNSLASIPGQSQRPLNNEMYSAFKSG--NVVKGILCPSLTNS 306
            ||   |..|..||        |||..|              .|.:|:.|  .:|||::..:....
 Worm   119 GP---TFQCEPFG--------ESGLKL--------------HYFSFRQGLFPIVKGLVRKTARTL 158

  Fly   307 F----KQSSLERSYLTYTHRQRQKSLIIVNVVDFVLKIVLAFVWIMRRSELGPIESDDG------ 361
            |    |...|||      :::|:||.::.:|:                   ..:|.||.
 Worm   159 FEMDVKVCMLER------NQERRKSGMVEHVI-------------------FSVEPDDNHRKGKR 198

  Fly   362 ----------TSMATAITWS--VCCGIANMAICFLGYWRCFANNYLHWAAVCTWVLFNIQGFVGQ 414
                      |..|.:.|.|  :..|:.:....| .|..|| |..:        ::.:|..::.:
 Worm   199 LFHKFRNTKTTENAPSFTLSSTILVGLRDFKNIF-PYHVCF-NKQM--------IIEHIGIYLLR 253

  Fly   415 GVGFADREYLVWYILFVIFVPYAMLPLPLKWCVVGGTITASCHLAVITIIKLQH----------- 468
            ..|..:::.|....|..:..| :.:.|..|        ....:|..:.|.:|:|
 Worm   254 EYGLENKKTLKVSDLMQLVQP-SDIQLTYK--------NVLSYLNTLFIFQLKHHSKRNEVQEGS 309

  Fly   469 -------------------GEATI---NPECVLFQIFANFILYTAINVAGMYTKYLTDRGQ-RLA 510
                               |.:.|   :|.....:...|..||.:.......|:.|....| |:.
 Worm   310 SEAFQQPLVLKGEMMPINDGNSIIFICSPHVTTVRDILNLKLYISDMPMHDATRDLVMLNQSRIC 374

  Fly   511 FIETHKAMEH-----KK---ESEKELQRTQKLLDSILPNIVNNQIRSEMYKGTDPTVETQFNKLY 567
            .:|.:|.:|.     ||   |.|.:..:|.:||...:|.::...:|:.      .||..|
 Worm   375 QMELNKKLEETMKKMKKMTEELEVKKSQTDRLLFEFVPPVIAEALRAA------KTVPAQ----- 428

  Fly   568 VYPMDNVSILFADIKGFTELASKTSAQQLVKILNDLFARFDRIAEDNHCLRVKLLGDCYYCVSQF 632
              ...:.|::|.||..|..::...|..:::.::.|||.|||||.|.:...:|..|.|.|..|...
 Worm   429 --EFSDCSVIFTDIPDFFTISVNCSPTEIITVVTDLFHRFDRIIEKHKGYKVLSLMDSYLIVGGV 491

  Fly   633 ESDNWKTRPDHAVCSVETGLHMIKAIKDV---RLHTHVDLNMRIGIHSGSVMCGVLGNKKWHFDV 694
            .:.|    ..|...|:...|.::...|.|   :|...|  .:|||:|.|.|:.|::..:|..|.|
 Worm   492 PNAN----QYHCEDSLNLALGLLFEAKQVVVPKLERSV--RLRIGVHCGPVVAGIVSQQKPRFCV 550

  Fly   695 WSNDVIIANHMESGGIPGRVHISEAT-------LKCL-----NDAYEVEPGNGGCRDNHLKMLNV 747
            ..|.|.:...:.|...||:|.:|.|.       ||.:     |...|::.|            .|
 Worm   551 LGNTVNVTKSICSHSSPGKVLVSNAVRTMVTKHLKSIFVFNANGYLELQSG------------KV 603

  Fly   748 KTYLIKRTE 756
            .|:.:::.|
 Worm   604 LTHFLEKNE 612

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ac78C	NP_001262138.1	AC_N	<288..551	CDD:292831	60/328 (18%)
		CYCc	526..729	CDD:214485	57/217 (26%)
		Guanylate_cyc	566..753	CDD:278633	53/201 (26%)
		DUF1053	929..1020	CDD:283888
		CYCc	1353..1554	CDD:214485
		Guanylate_cyc	1381..1576	CDD:278633
gcy-37	NP_500171.2	HNOB	3..165	CDD:285002	17/70 (24%)
		HNOBA	223..419	CDD:285003	38/214 (18%)
		CYCc	400..577	CDD:214485	54/195 (28%)
		Nucleotidyl_cyc_III	425..609	CDD:299850	55/208 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810