Protein Alignment Ac78C and gcy-36

DIOPT Version :10

• Sequence 1: NP_001262138.1
• Gene: Ac78C / 40333
• FlyBaseID: FBgn0024150
• Length: 1727
• Species: Drosophila melanogaster
• Sequence 2: NP_510557.3
• Gene: gcy-36 / 191657
• WormBaseID: WBGene00001556
• Length: 675
• Species: Caenorhabditis elegans
• Alignment Length: 313
• Identity: 89/313 - (28%)
• Similarity: 138/313 - (44%)
• Gaps: 51/313 - (16%)

  Fly  1285 MMKFGSGDSF---------SLVELSRLG-----MPL--GVQMLILLISFLVMVCYHARLVEVTSR 1333
            ||...||...         |:.||.:.|     ||:  ..:.||||        ...||.:|...
 Worm   339 MMLMSSGGHIMYLCSPYVTSIPELLQYGLRLTAMPIHDPTRDLILL--------NQQRLSDVEMN 395

  Fly  1334 LDF-IWKEQAERELTNMKSNRALNDTLIKNILPDHVATYY---LSDEHTDELYSKMHNLCGVMFA 1394
            |.. ...||.|....:::..:...|.|::.:||..||...   ||.|      ::.:....|||.
 Worm   396 LQLEANNEQLENMAKDLEVEKGKTDALLREMLPPSVAQQLKQGLSVE------AREYEEATVMFT 454

  Fly  1395 SIPNFQDFYSEDIDNGKACIRILNEIICDFDELLEEPRFASVEKIKTVGATYMAAAGLNHEHLRL 1459
            .:|.||...  .:...|..:.:|||:...||.|:   ......|::|||.:||:..|:
 Worm   455 DVPTFQQIV--PLCTPKDIVHLLNELFTKFDRLI---GIQKAYKVETVGDSYMSVGGI------- 507

  Fly  1460 RGETSEDSVCDLV-EFAFAMKQKLEEINGDAFNN-FQLRVGICSGPLVSGVIGARKPVYDIWGNT 1522
              ....|..|::: ..|..|..:...:.....|. ..:|.||.|||:|:||:||:.|.|.::|:|
 Worm   508 --PDLVDDHCEVICHLALGMVMEARTVCDPITNTPLHIRAGIHSGPVVAGVVGAKMPRYCLFGDT 570

  Fly  1523 VNVASRMDSTGENWRVQVPENTAELLCSRG-YTCVKRGEIAVKGKGMMTTFYV 1574
            ||.:|||:|.....|:...||..:...|.| :....||.:.:||||.|.|:::
 Worm   571 VNTSSRMESHSPIGRIHCSENAKKCAESTGRFEFEPRGRVQIKGKGEMNTYFL 623

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ac78C	NP_001262138.1	AC_N	<216..551	CDD:318454
		Guanylate_cyc	566..753	CDD:425528
		Adcy_cons_dom	929..1021	CDD:461877
		Guanylate_cyc	1381..1576	CDD:425528	59/197 (30%)
gcy-36	NP_510557.3	HNOB	3..167	CDD:462233
		HNOBA	217..435	CDD:462234	27/103 (26%)
		CYCc	415..604	CDD:214485	60/208 (29%)