Protein Alignment Ac78C and gcy-21

DIOPT Version :10

• Sequence 1: NP_001262138.1
• Gene: Ac78C / 40333
• FlyBaseID: FBgn0024150
• Length: 1727
• Species: Drosophila melanogaster
• Sequence 2: NP_001364740.1
• Gene: gcy-21 / 191651
• WormBaseID: WBGene00001546
• Length: 1163
• Species: Caenorhabditis elegans
• Alignment Length: 291
• Identity: 83/291 - (28%)
• Similarity: 143/291 - (49%)
• Gaps: 43/291 - (14%)

  Fly  1295 SLVELSRLGMPLGVQMLILLISFLVMVCYHARLVEVTSRLDFIWKEQAERELTNMKSNRALNDTL 1359
            ||.::.|...||.:.:...::..:|     :.:.:.|.:|:   |:.|||. ..::..:|.::.|
 Worm   870 SLHQIKRKLKPLTIGLKRTIMDNMV-----SMIEKYTDKLE---KDIAERN-EELEGEKAKSEAL 925

  Fly  1360 IKNILPDHVA-TYYLSDEHTDELYSKMHNLCGVMFASIPNFQDF--YSEDIDNGKACIRILNEII 1421
            :|.:||:.|| :..|....:.|.:..    |.|.|:..|.|.:.  .|:.||    .::.||::.
 Worm   926 LKMMLPEVVADSLKLGSNVSAESFEN----CTVFFSDCPGFVEMSATSKPID----IVQFLNDLY 982

  Fly  1422 CDFDELLEEPRFASVEKIKTVGATYMAAAGL-----NHEHLRLRGETSEDSVCDLVEFAFAMKQK 1481
            ..||.::::   ..|.|::|:...||.|:||     ||.    .||        :.....|:.:.
 Worm   983 TVFDRIIDQ---FDVYKVETIADAYMVASGLPVPNGNHH----AGE--------IASLGLALLKA 1032

  Fly  1482 LEEINGDAFNN--FQLRVGICSGPLVSGVIGARKPVYDIWGNTVNVASRMDSTGENWRVQVPENT 1544
            :|........|  .:||:|:.|||.|:||:|.:.|.|.::|:|||.||||:|.|...|:......
 Worm  1033 VESFKIRHLPNEKVRLRIGMNSGPCVAGVVGLKMPRYCLFGDTVNTASRMESNGIPLRINCSGTA 1097

  Fly  1545 AELLCS-RGYTCVKRGEIAVKGKGMMTTFYV 1574
            .|:|.. .||...:||.:.:||||...|::|
 Worm  1098 KEILDQLGGYEIEERGIVEMKGKGKQMTYFV 1128

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ac78C	NP_001262138.1	AC_N	<216..551	CDD:318454
		Guanylate_cyc	566..753	CDD:425528
		Adcy_cons_dom	929..1021	CDD:461877
		Guanylate_cyc	1381..1576	CDD:425528	62/204 (30%)
gcy-21	NP_001364740.1	Periplasmic_Binding_Protein_type1	58..422	CDD:471960
		PK_GC	612..881	CDD:270894	3/10 (30%)
		HNOBA	<890..938	CDD:462234	14/56 (25%)
		Guanylate_cyc	944..1130	CDD:425528	63/208 (30%)