DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10565 and Dnajc18

DIOPT Version :9

Sequence 1:	NP_001246856.1	Gene:	CG10565 / 40332	FlyBaseID:	FBgn0037051	Length:	646	Species:	Drosophila melanogaster
Sequence 2:	NP_083945.1	Gene:	Dnajc18 / 76594	MGIID:	1923844	Length:	357	Species:	Mus musculus

Alignment Length:	336	Identity:	74/336 - (22%)
Similarity:	123/336 - (36%)	Gaps:	123/336 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 QRRQFLAPGGVERSESDEKLEGVGEEVDISYLKSLDPKEWKDQDHYAVLGLGKLRYEASEDDVRR 97
            |.||    |....:.::|:|.||      ..:|       |.:::|.:||:.   :.||::::::
Mouse    56 QTRQ----GEGNATYTEEQLRGV------QRIK-------KCRNYYDILGVS---HNASDEELKK 100

  Fly    98 AYRRMVLLHHPDKRKAKGEEVIQDDDYFTCITKAYEILGTSKPRRSFDSV-DPEFDDSLPS---- 157
            ||:::.|..||||..|.|.     .:.|..|..|:.:|.....|..:|.. |.:...::|.
Mouse   101 AYKKLALKFHPDKNCAPGA-----TEAFKAIGNAFAVLSNPDKRLRYDEYGDEQVTFTVPRARSY 160

  Fly   158 ------QNDIDNDYFGVFNKFFTLNGRWSEKPHVPS-----FGQV--DA---------------K 194
                  :.||..:  .:||.||  .|      |.||     |..|  |:               |
Mouse   161 HYYKDFEADISPE--ELFNVFF--GG------HFPSGNIHMFSNVTDDSQYYRRRHRHERTQTHK 215

  Fly   195 REE----------------------------------VERFYNFWYDFKSWREFS------YLDE 219
            |||                                  ...||.....:...||..      ::|:
Mouse   216 REEDKSQTPYSAFVQLLPVLVIVTISVITQLLAANPPYSLFYKSTLGYTISRETQNLQVPYFVDK 280

  Fly   220 E-DKE-KGQD-RDERRWIEK------ENRAARIKRKKEEMSRIRSLVDLAYNNDKRIQRFKQEEK 275
            . ||. :|.. ||..:.|||      :....:.|::|.|::.:..|.     .|:|: |.|.|..
Mouse   281 NFDKAYRGASLRDLEKTIEKDYIDYIQTSCWKEKQQKSELTNLAGLY-----RDERL-RQKAESL 339

  Fly   276 DRKAAAKRAKM 286
            ..:..||.:|:
Mouse   340 KLENCAKLSKL 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10565	NP_001246856.1	CbpA	76..282	CDD:225124	61/287 (21%)
		DnaJ	76..145	CDD:278647	19/68 (28%)
		RILP-like	268..>344	CDD:304877	6/19 (32%)
		RAC_head	332..401	CDD:293322
		SANT	584..633	CDD:197842
		SANT	585..632	CDD:238096
Dnajc18	NP_083945.1	PRK14298	81..>182	CDD:184612	28/112 (25%)
Dnajc18	NP_083945.1	DUF1977	250..349	CDD:370429	24/104 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847135
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840