DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10565 and CG17187

DIOPT Version :9

Sequence 1:	NP_001246856.1	Gene:	CG10565 / 40332	FlyBaseID:	FBgn0037051	Length:	646	Species:	Drosophila melanogaster
Sequence 2:	NP_650056.1	Gene:	CG17187 / 41351	FlyBaseID:	FBgn0037882	Length:	299	Species:	Drosophila melanogaster

Alignment Length:	347	Identity:	73/347 - (21%)
Similarity:	131/347 - (37%)	Gaps:	108/347 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 KEWKDQDHYAVLGLGKLRYEASEDDVRRAYRRMVLLHHPDKRKAKGEEVIQDDDYFTCITKAYEI 134
            |::.|.:.|.:||:.   .|:.::::|:|||:..|..||||.....:.|    :.|..::||.||
  Fly     4 KKYSDVNLYDLLGIS---LESDQNEIRKAYRKKALECHPDKNPDNPKAV----ERFHELSKALEI 61

  Fly   135 LGTSKPRRSFDSVDPEFDDSLPSQNDIDNDYFGVFNKFFTLNGRWSEKPHVPSFGQVDAKREEV- 198
            |.....|.::|.|       |.::            |...|..|           |:|.||:::
  Fly    62 LTDESARAAYDKV-------LKAK------------KAAELRSR-----------QLDGKRQKLK 96

  Fly   199 ----ERFYNFWYDFKSWREFSYLDEEDKEKGQDRDER------RWIEKENRAARIKRKKEEMSRI 253
                ||.....:.....:.:|.:.:.|:|...::.||      |.:|:|.||     .:|:..|
  Fly    97 LELEERERAALHKLAKSQPYSTVAKSDEEVLHEQIERLRREGSRLLEEEQRA-----MQEQFRR- 155

  Fly   254 RSLVDLAYNNDKRIQRFKQEEKDRKAAAKRAKM--------DAAQAQ------------------ 292
                     |....|:.:|:.....:|..|.||        |..|.:
  Fly   156 ---------NHAEQQKLQQQPVQFDSAQHRIKMKWKAEPGQDYTQQELLKYLKKYGDVVALVVNS 211

  Fly   293 ----KAEADRAIREA---ALAKEKAEKAEQKRIEQIRIEREQQKKLLKKERKTLRDKVKDCKYYA 350
                :|..:.|.|||   .||.||.:.|:....|.:...        ..:::|.:.....|...:
  Fly   212 KRRGRAMVELATREACDMVLAYEKGDPAKPLHFEWVTPP--------AADKQTTKSATTGCSASS 268

  Fly   351 KNDKD----QLKHMEGTEKICE 368
            .:.:|    :|:..|..:::.|
  Fly   269 TDYEDLVMRKLRQAEERKRLIE 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10565	NP_001246856.1	CbpA	76..282	CDD:225124	49/216 (23%)
		DnaJ	76..145	CDD:278647	21/68 (31%)
		RILP-like	268..>344	CDD:304877	20/108 (19%)
		RAC_head	332..401	CDD:293322	6/41 (15%)
		SANT	584..633	CDD:197842
		SANT	585..632	CDD:238096
CG17187	NP_650056.1	DnaJ	10..72	CDD:278647	21/68 (31%)
CG17187	NP_650056.1	RRM_DNAJC17	175..247	CDD:240875	16/71 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464428
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930