DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10565 and CG2790

DIOPT Version :9

Sequence 1:	NP_001246856.1	Gene:	CG10565 / 40332	FlyBaseID:	FBgn0037051	Length:	646	Species:	Drosophila melanogaster
Sequence 2:	NP_611986.2	Gene:	CG2790 / 37992	FlyBaseID:	FBgn0027599	Length:	540	Species:	Drosophila melanogaster

Alignment Length:	561	Identity:	122/561 - (21%)
Similarity:	208/561 - (37%)	Gaps:	166/561 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 KLRYEASEDDVRRAYRRMVLLHHPDKRKAKGEEVIQDDDYFTCITKAYEILGTSKPRRSFDSVDP 149
            :|:..|::.|::.|||:|.|..||||..   :.:.:..:.|..|.:|||:|...:.|..:|:
  Fly     9 ELQRNANDGDIKSAYRKMALRWHPDKNP---DRLAEAKERFQLIQQAYEVLSDPQERSWYDN--- 67

  Fly   150 EFDDSLPSQN-DIDNDYFGVFNKFFTLN--GRWSEKPH--------------------------- 184
            ..:..|..:| |...:...|| :|||.:  ..:.:..|
  Fly    68 HREQILRGKNSDYAENCLDVF-QFFTSSCYKGYGDNEHGFYRVYTDVFVQIASEDLEFMDKDDRL 131

  Fly   185 --VPSFGQVDAKREE-VERFYNFWYDFKSWREFSYLDEEDKEKGQDRDERRWIEKENRAARIKRK 246
              .|.||..::..|: |..||.||..:.:.:.:.:|...|..:.::|...|.:|||.:......:
  Fly   132 GMAPDFGHSNSSYEDVVGPFYAFWQAYSTRKTYDWLCPYDVREIKERFILRKVEKEMKKIVQAAR 196

  Fly   247 KEEMSRIRSLVDLAYNNDKRIQ-------------RFKQEEKDRKAAAKRAKMDAAQAQKAEADR 298
            ||....:|:||:.....|.|:|             |.|||||.::...||      |.:.|
  Fly   197 KERNEEVRNLVNFVRKRDPRVQAYRRMLEERVEANRLKQEEKRKEQLRKR------QEELA---- 251

  Fly   299 AIREAALAKEKAEKAEQKRIEQIRIEREQQKKLLKKERKTLRDKVKD------------------ 345
            |:|:..:..|..|       ||:: :.|||.. .|.|..|..|:..|
  Fly   252 AVRKNNVFNEGYE-------EQLK-QLEQQYD-SKSEDYTDEDENDDDGEDFDHEGGQEAEEYEV 307

  Fly   346 ----------CKYYAKNDK------DQLKHMEGTEKICETFNLAELQALNKAMESK--GRESFVA 392
                      |....||.|      :..||.|..:::|:.....|....|:..|..  |.:..:.
  Fly   308 EYVDDLYCVACNKTFKNAKARANHEESKKHNENVDRLCQEMEEEEDAFHNEPHEDSLMGVQESLE 372

  Fly   393 ALQTAEQKIAAELEEINQTQAKKLASSAATPKGVKEVKKNELWSNENVQLLIKAVNLFPAGTAQR 457
            .||.:|.:|:  .:.:...:...||         |..|||:......|:          ...|:.
  Fly   373 ELQVSEDQIS--FDGVPSEEESSLA---------KRTKKNKKARKSAVK----------QAQAEG 416

  Fly   458 WDVIATFINQHSPDNTVLVNARDVLNKAKALQNTDHSKSSLKTQANDAAFA----SFEKSKKDVQ 518
            .|         .||..:                   .|.::|:::.|..::    :.:|||....
  Fly   417 SD---------EPDEPI-------------------EKKAIKSESEDEDWSKGKKASKKSKSKKT 453

  Fly   519 TCKDITLGEETAQASKENLKQNGVDHKANNQS---TKQNGT 556
            |.:.:.|.|:|  .|:.|.|:..|..|:.::.   ||...|
  Fly   454 TTRKVKLLEQT--VSEPNTKEATVAPKSGDEDLDPTKSQHT 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10565	NP_001246856.1	CbpA	76..282	CDD:225124	59/242 (24%)
		DnaJ	76..145	CDD:278647	19/59 (32%)
		RILP-like	268..>344	CDD:304877	24/88 (27%)
		RAC_head	332..401	CDD:293322	20/104 (19%)
		SANT	584..633	CDD:197842
		SANT	585..632	CDD:238096
CG2790	NP_611986.2	DnaJ	3..66	CDD:278647	19/59 (32%)
		ZUO1	19..>252	CDD:227594	60/249 (24%)
		zf-C2H2_jaz	313..337	CDD:288983	4/23 (17%)
		C2H2 Zn finger	315..337	CDD:275371	4/21 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464410
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840